How Altered Gut-Brain-Axis Influences Food Choices. (BrainFood) Part 2: Digital Receipts
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 61
- 试验地点
- 2
- 主要终点
- Changes in food purchase behaviour on the basis of food groups
研究概览
简要总结
Obesity is currently one of the most substantial health burdens. Due to the production of marked and sustained weight loss, bariatric surgery is an increasingly used therapeutic modality to combat obesity and its comorbidities. Surgical rearrangement of the gastrointestinal tract remarkably alters metabolism and hormones acting on neurological and hypothalamic signalling, involved in food decision-making and eating behaviour. In this context, many patients who underwent bariatric surgery self-report changes in appetite, satiety and food preferences. Furthermore, new gut hormone-based (e.g. GLP-1 receptor agonist or GLP-1-RA) pharmacotherapies which mimic the effect of bariatric surgery show impressive efficacy on weight reduction by modulation of food behaviour. However, the mechanisms of such functional changes, and how they relate to food decision-making and food purchase behaviour remain unknown.
In Part 2 of the BrainFood-project, the investigators propose a novel approach using digital receipts from loyalty card to unravel the effect of obesity treatments (surgical and non-surgical) on eating and food purchase behaviour in daily life.
详细描述
The overall aim of this project is to elucidate the changes in food behaviour among obese adults undergoing obesity treatments.
The main objective is to observe the effect of obesity treatments on food purchase behaviour using digital receipts from grocery shopping. The investigators hypothesize that bariatric surgery leads to changes in food purchase behaviour in obese adults.
The further objective is to compare food purchase behaviour between obese adults against values of an existing reference population, and to assess whether these differences tend to be reduced after the start of the treatment among obese participants.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Female and male subjects aged 18 years or older
- •Proficient in German (including written)
- •BMI≥30kg/m2 or BMI≥28kg/m2 with adiposity-related comorbidities (prediabetes, type 2 diabetes mellitus, hypertension, dyslipidemia)
- •Referred for obesity treatment or who started obesity treatment within 6 months (surgical or non-surgical)
- •Primary grocery shopping at the Swiss biggest grocery retailers (Coop, Migros), and regularly using a loyalty card (Cumulus and/or Supercard)
排除标准
- •Incapacity to give informed consent
- •Primary shopping in other food retailers (e.g. Aldi, Lidl, outside of Switzerland, etc.)
研究组 & 干预措施
Obesity treatment Group
60 (minimum) to 150 (maximum) overweight/obese adults referred for or who started obesity (surgical or non-surgical) treatment within 6 months
干预措施: Questionnaire (Survey and Food Frequency Questionnaire (FFQ)) (Other)
Obesity treatment Group
60 (minimum) to 150 (maximum) overweight/obese adults referred for or who started obesity (surgical or non-surgical) treatment within 6 months
干预措施: Collection of digital receipts from grocery shopping (Other)
Control Group
Comparison of food purchase behaviour with control subjects will be performed using an already existing cohort from a previous study. This does not required recruiting control subjects.
结局指标
主要结局
Changes in food purchase behaviour on the basis of food groups
时间窗: Pre-treatment until 5 years after start of obesity treatment
Changes in food purchase behaviour pre-treatment will be compared to post-treatment on the basis of food groups like vegetables, wholegrain, fruits, sweets and meats.
Changes in food purchase behaviour on the basis of the Healthy Trolley Index (HETI)
时间窗: Pre-treatment until 5 years after start of obesity treatment
Changes in food purchase behaviour pre-treatment will be compared to post-treatment on the basis of the HETI, an objective and validated, nutrient-based, healthy shopping scoring system.
Changes in food purchase behaviour on the basis of the Grocery Purchase Quality Index (GPQI)
时间窗: Pre-treatment until 5 years after start of obesity treatment
Changes in food purchase behaviour pre-treatment will be compared to post-treatment on the basis of the GPQI, an objective and validated, nutrient-based, healthy shopping scoring system.
Food purchase behaviour on the basis of food groups
时间窗: Pre-treatment until 5 years after start of obesity treatment
Food groups will be compared between obesity treatment group and control group
Food purchase behaviour on the basis of nutrition facts
时间窗: Pre-treatment until 5 years after start of obesity treatment
Nutrition facts will be compared between obesity treatment group and control group
Changes in food purchase behaviour on the basis of nutrition facts
时间窗: Pre-treatment until 5 years after start of obesity treatment
Changes in food purchase behaviour pre-treatment will be compared to post-treatment on the basis of nutrition facts like energy (kcal), carbohydrates, sugars, added sugars, protein, fat, saturated fat, dietary fibre and salt.
Food purchase behaviour on the basis of the Healthy Trolley Index (HETI)
时间窗: Pre-treatment until 5 years after start of obesity treatment
HETI will be compared between obesity treatment group and control group
Changes in food purchase behaviour on the basis of the Nutri-Score
时间窗: Pre-treatment until 5 years after start of obesity treatment
Changes in food purchase behaviour pre-treatment will be compared to post-treatment on the basis of the Nutri-Score, representing the nutritional quality of products. The Nutri-Score is based on a discrete continuous scale from -15 (most healthy) to 40 (least healthy). The score is then transcribed into five colour categories (A-E, ranging from bright green (most healthy) to red (least healthy)).
Food purchase behaviour on the basis of the Grocery Purchase Quality Index (GPQI)
时间窗: Pre-treatment until 5 years after start of obesity treatment
GPQI will be compared between obesity treatment group and control group
Food purchase behaviour on the basis of the Nutri-Score
时间窗: Pre-treatment until 5 years after start of obesity treatment
Nutri-Score will be compared between obesity treatment group and control group
次要结局
未报告次要终点
研究者
Lia Bally
Professor
Insel Gruppe AG, University Hospital Bern