A Study for Discovering Biomarker Candidates of Idiopathic Parkinson's Disease - A Pilot Study
- Conditions
- Diseases of the nervous system
- Registration Number
- KCT0004717
- Lead Sponsor
- Gachon University Gil Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
1) Parkinson's disease (experimental group)
-Those who have not been diagnosed with dementia among Parkinson's disease outpatients of Gil Medical Center Neurology
-Criteria of UK Parkinson's Diseases Society Brain Bank Criteria
-40 years old and over, total 15 people
2) Control group
-Have no family history of movement disorder
-Persons who do not meet other exclusion criteria
-40 years old and over, total 15 people
1) The following people are excluded from the experimental group
• Pregnant women
• Women who are currently breastfeeding
• Patients with poor condition that are difficult to perform the test
• Patients with brain diseases other than Parkinsonism
• Persons deemed inappropriate by the clinical researcher in addition to the above items.
2) The following people are excluded from the control group.
• Pregnant women
• Women who are currently breastfeeding
• Staff or students in the same institution
• Patients with poor condition that are difficult to perform the test
• Patients serious psychiatric problems
• Patients with abnormal cognitive function due to the presence of central nervous system disease or sequelae of previous neurological diseases
• Anyone with abnormal findings on brain MRI or PET in the past
• Patients with brain diseases
• Persons deemed inappropriate by the clinical researcher in addition to the above items.
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method RNA expression difference between the control and experimental groups
- Secondary Outcome Measures
Name Time Method RNA expression profiling of samples