CTRI/2024/10/075351尚未招募4 期
Comparison of oral Dexamethasone and Prednisolone in Acute Bronchial Asthma: A Randomized Controlled Trial
Department of Pediatrics Government Multi specialty hospital Chandigarh1 个研究点 分布在 1 个国家目标入组 82 人开始时间: 2024年11月1日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- Comparison of improvement in PRAM score
研究概览
简要总结
Comparison of oral Dexamethasone and Prednisolone in Acute Bronchial Asthma in children: A Randomized Controlled Trial.
Data will be collected during hospitalization period and patient will; be reviewed after 7 days.
The patients will receive either oral dexamethasone for 2 days or oral prednisolone for 5 consecutive days in addition to the standard treatment. Length of hospital stay and number of Emergency department revisits within next 7 days after discharge will be compared between two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 2.00 Year(s) 至 12.00 Year(s)（—）
- 性别
- All
入选标准
- •Children between the ages of 2-12 years hospitalized with at least one previous exacerbation of wheeze or a known case of asthma.
排除标准
- •Contraindication for use of dexamethasone or prednisolone.
- •Significant medical comorbidity: Congenital and acquired heart disease, chronic lung disease, tuberculosis, cholestatic jaundice.
- •Life threatening exacerbation requiring PICU admissions.
- •Children already enrolled in the study and presenting within 60 days of discharge from hospital.
结局指标
主要结局
Comparison of improvement in PRAM score
时间窗: At admission, 12 hours, 24 hours
次要结局
- Comparison of length of hospital stay between 2 groups.(0 to 14 days)
- Comparison of recurrence of symptom.(on day 7 after discharge)
- Need for additional steroid in dexamethasone group.(within 24 hours)
研究者
Dr Sajal Choudhary
Government Multi specialty Hospital, sector 16 , Chandigarh
研究点 (1)
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