Effect of phenytoin mucoadhesive paste 1% on periodontal parameters
- Conditions
- Chronic periodontitis.Chronic periodontitis
- Registration Number
- IRCT2014081718834N1
- Lead Sponsor
- Vice chancellor for research of Shahid Sadoughi Dental Faculty
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion criteria were considered as follows: having ability to read and write, no systemic diseases such as diabetes or heart disease, not taking medications affecting periodontium (anti- hypertensives, immune suppressants and anticonvulsants), not being pregnant, no smoking, no traumatic occlusion, no history of antibiotic therapy within the last three months, having at least two similar teeth on each sextants without any decays or restorations and filling informed consent form. In addition we consulted with internist about any drug interactions to phenytoin in patients of our study. The exclusion criteria were considered as follows: 1) inappropriate control plaque during the study. 2) irregular use of pastes on the basis of given instructions 3) not taking part in following up appointments.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pocket depth. Timepoint: 4 weeeks. Method of measurement: milimeters by Williams’s periodontal probe.;Bleeding on probing. Timepoint: 4 weeks. Method of measurement: percentage.;Modified gingival index. Timepoint: 4 weeks. Method of measurement: grading by observation.
- Secondary Outcome Measures
Name Time Method