Effect of mycophenolate mofetil on oral erosive lichen planus
Phase 2
- Conditions
- Oral lichen planus.lichen planus
- Registration Number
- IRCT2013011611976N2
- Lead Sponsor
- Deputy of Research of Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
patients with erosive oral lichen planus with clinical manifestations and histopathological criteria; existence of two lesions with similar clinical appearance on the right and left buccal mucosa; patients older than 18 years of age.
Exclusion criteria: not received any treatment for the lesions for at least 4 weeks ago; any factor that cause lichenoid reaction; any systemic or dermal disease which affects immune system of the patient; incidence of any adverse effect of mycophenolate mofetil during the study
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Size of lesion. Timepoint: Baseline and after 1 month. Method of measurement: Measured by digital culis.;Pain and burning sensation. Timepoint: Baseline and weekly for one month. Method of measurement: The oral lesions will be clinically graded based on VAS grading scale.
- Secondary Outcome Measures
Name Time Method Adverse effects. Timepoint: Evrey week for 1 month. Method of measurement: Clinical examination.