Effect of Topical Mycophenolate, Zinc and Aloe vera in oral lichen planus ulcers
Phase 3
- Conditions
- Oral lichen planus.oral lichen planusl43.8
- Registration Number
- IRCT20200708048057N1
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
Age over 18 years
A patient who is diagnosed with lichen planus on pathological examination.
Willingness to participate in the study
Existence of a bilateral lesion
Exclusion Criteria
Pregnant and lactating women
Systemic use of corticosteroids
High blood pressure
Smokers
All items where topical corticosteroids are contraindicated, such as: uncontrolled diabetes, history of tuberculosis, gastric ulcer
Adjacent waste with amalgam filling
Systemic diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Size of erythema and ulcer. Timepoint: 15 days after treatment. Method of measurement: dental micrometer (colis) .
- Secondary Outcome Measures
Name Time Method Pain and burning. Timepoint: 15 days after receiving the drug. Method of measurement: visual analog scale (VAS).
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the synergistic effects of mycophenolate mofetil, zinc, and aloe vera in treating oral lichen planus lesions?
How does the efficacy of mucoadhesive polymeric scaffolds with aloe vera, zinc, and mycophenolate compare to corticosteroids in phase III oral lichen planus trials?
Which biomarkers correlate with response to mycophenolate mofetil-based mucoadhesive scaffolds in oral lichen planus subtypes?
What adverse events are associated with mucoadhesive polymeric scaffolds containing mycophenolate mofetil, zinc, and aloe vera in oral lichen planus phase III trials?
What are the comparative advantages of mucoadhesive scaffolds with mycophenolate mofetil, zinc, and aloe vera over tacrolimus in oral lichen planus treatment?