Evaluation of Sodium Bicarbonate Effect on Contrast-induced Acute Kidney Injury Following Diagnostic Coronary Angiography

Phase 3

• Conditions: Condition 1: Ischemic heart diseases. Condition 2: Ischemic heart diseases. Condition 3: Ischemic heart diseases. Condition 4: Ischemic heart diseases. Condition 5: Ischemic heart diseases.; Angina pectoris; Acute myocardial Infarction; Other acute ischemic heart diseases; Chronic ischemic heart disease; Subsequent myocardial infarction

• Registration Number: IRCT2013050813115N1
• Lead Sponsor: Vice chancellor for research, Kermanshah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 158

Inclusion Criteria

The major inclusion criteria include creatinin level greater than 1.5 mg/dl in men and greater than 1.4 mg/dl in women; creatinin clearance less than 60 ml/min/1.73 m2; older than 18-year-old; and history of diabetes mellitus for more than one year.

The exclusion criteria include cardiogenic shock; heart failure; acute coronary syndrome recently undergone angiography or angioplasty; recent dialysis; single kidney; and any infusion of contrast media such as radiologic interventions.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Creatinine. Timepoint: prior angiography and at 48 hours after angiography. Method of measurement: Serum level, mg/dl.

Secondary Outcome Measures

Name	Time	Method
Creatinin change. Timepoint: Prior angiography and 48 hours after angiography. Method of measurement: serum level, mg/dl.