Evaluation of the effect of oral sodium bicarbonate on the symptoms of overactive bladder and acidic urine

Phase 2

Recruiting

Conditions: over active bladder.
Overactive bladder
N32.81

Registration Number: IRCT20131203015634N3

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 36

Inclusion Criteria

Patients referred to the gynecology clinic included all patients over 18 years of age who voluntarily and knowingly complained of overactive bladder symptoms who had these symptoms for at least 12 weeks and received no treatment, had a frequency of more than 8 times and more than 2 times nocturia, urinary pH less than 6 and lacked of relaxation. Patients under 18 years of age, urinary pH more than 6, kidney stones, stress incontinence, history of abdominal menopause surgery, heart problems, urinary tract infections, malignancies, pelvic pain, neurogenic bladder , Use of antidepressants, anticholinergics, alphablockers, beta-3 agonists, and history of allergies to anticholinergics, sodium bicarbonate, rectocell, cystocell, and uterine prolapse, frequency Less than 8 and nocturia less than 2 in 24 hours are not included in the study.

Exclusion Criteria

If the patient does not want to continue taking. Allergic reaction to the drug. The patient becomes pregnant. Reluctance to continue cooperation in the project. They are excluded from the study.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
OVER ACTIVE BLADDER SCORE POINT. Timepoint: One month after taking the drug. Method of measurement: questionnaire OAB-V8.;URINE PH. Timepoint: Before administration of tolterodine and sodium bicarbonate at the beginning of the study and one month after receiving tolterodine and sodium bicarbonate. Method of measurement: urine dipstick.;Oab-v8 questionnaire score based on score before and after receiving tolterodine and sodium bicarbonate. Timepoint: Before administration of tolterodine and sodium bicarbonate at the beginning of the study and one month after receiving tolterodine and sodium bicarbonate. Method of measurement: Scoring based on the score of the questionnaire.

Secondary Outcome Measures