MedPath

The effect of mouthwash on the treatment of oral mucositis

Phase 3
Recruiting
Conditions
cancer.
Carcinoma in situ of other and unspecified digestive organs
Registration Number
IRCT20190703044082N3
Lead Sponsor
Hamedan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
144
Inclusion Criteria

•Patients with cancer aged 18-65 years
•Stage I and II of Cancer
•Under chemotherapy
•With no oral ulcer
•To be able to carry out a mouthwash
•Having a normal level of white blood cells and platelets
•Not using another medication to prevent and treat oral mucositis
•Not being in pregnancy and lactation time
•Not receiving chemotherapy and radiotherapy simultaneously
•No other physical and mental disorders
•Insensitivity to zinc chloride and sodium bicarbonate
•Receiving at least one drug from the category of commonly used chemotherapy drugs
•Not receiving chemotherapy drugs which increase mucositis, such as actinomycin and ...

Exclusion Criteria

•Absence in at least one session of determined days for treatment follow-up
•Hypersensitivity to zinc chloride and sodium bicarbonate
•Extensive disability and weakness of the patient

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Treatment of oral mucositis. Timepoint: 1 day before the intervention and 1, 4, 7 and 14 days after the intervention. Method of measurement: Visual Analogue Scale, Oral mucositis index, World Health Organization criteria for grading of oral mucositis.
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath