The effect of acupuncture, hypericum perforatum and diet in appetite and weight control

Phase 3

Recruiting

• Conditions: obesity.; Obesity due to excess calories; E66.0

• Registration Number: IRCT201706107265N9
• Lead Sponsor: Vice chancellor for research, Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

Appetite score more than 5 according to visual analogue scale
Body mass index between 24.9 to 39.9
Women 18 years old to pre-menopause; men 18 to 60 years old
Failure to life style modification alone
Liver qi stagnation syndrome according to Chinese Medicine syndrome differentiation

Exclusion Criteria

Hypothyroidism, Cushing's syndrome, cancer, liver or kidney failure
Using drugs effective on appetite, weight and metabolism in the previous month
Using drugs that interfere with Hypericum perforatum such as protease inhibitors, amiodarone, anticoagulants, cyclophosphamide, cyclosporine, monoamine oxidase inhibitors, phenytoin, tacrolimus, tamoxifen and trazodone drug
Drug abuse or alcoholism
Breast-feeding, pregnancy or planning a pregnancy during the next two months
Having pacemaker or any other metal device inside the body due to the use of electroacupuncture and Bioelectrical Impedance Analyzer
disability to do recommended physical activity
Allergy to Hypericum perforatum or metal
Coagulation disorders
History of receiving acupuncture

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma nesfatin-1. Timepoint: Before intervention, Sixth week. Method of measurement: Laboratory: ELISA.;Appetite score. Timepoint: Before intervention, weeks 2, 4, 6, 24. Method of measurement: Visual Analogue Scale.;Body Mass Index. Timepoint: Before intervention, weeks 2, 6, 24. Method of measurement: Using the bioelectrical impedance analyzer; kg/m2.

Secondary Outcome Measures

Name	Time	Method
Waist circumference. Timepoint: Before intervention, weeks 2, 6, 24. Method of measurement: Using a tape measure; centimeters.;Hip circumference. Timepoint: Before intervention, weeks 2, 6, 24. Method of measurement: Using a tape measure; centimeters.;Body composition. Timepoint: Before intervention, weeks 2, 6. Method of measurement: Using the bioelectrical impedance analyzer.;Lipid profile. Timepoint: Before intervention, week 6. Method of measurement: Laboratory.;Liver enzymes. Timepoint: Before intervention, week 6. Method of measurement: Laboratory.;Blood glucose level. Timepoint: Before intervention, week 6. Method of measurement: Laboratory.;Adverse events. Timepoint: During the study period within 48 to 72 hours of incidence; week 6. Method of measurement: Study checklist.