Targeted Fluid Resuscitation in Septic Shock: A Comparative Study between Capillary Refilling Time and Venous to Arterial PCO2
Not Applicable
- Conditions
- management of septic shock patients in ICU
- Registration Number
- PACTR202307764415273
- Lead Sponsor
- Ahmed Ismail
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
•Adult patients (aged 21-60 years) with septic shock.
•Serum lactate>2 mmol/liter.
•Requirements of norepinephrine (NE) to maintain a mean arterial pressure (MAP)=65 mmHg after an intravenous fluid load of 20 ml/kg over 60 min.
•Patients had to be recruited within a period of 24 h after septic shock diagnosis.
Exclusion Criteria
•Pregnancy.
•Peripheral vascular disease.
•Anticipated surgery or dialysis.
•Procedure during the first 6 h after potential inclusion.
•Active bleeding.
•Child B or C liver cirrhosis.
•Severe acute respiratory distress syndrome (ARDS).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum lactate measurement within ,first 6 hours intervention period
- Secondary Outcome Measures
Name Time Method 1-24 h SOFA score.<br>2. fluid volume administrated during the 6 hours intervention period <br><br>