eurosurgical Sepsis And Septic Shock Protocols After Craniotomy Clinical Outcomes And Survival Analysis.
Phase 1
Completed
- Conditions
- Central nervous system infection is a factor associated with an increase in perioperative mortality. Post-operative neurosurgical infection still highly prevalent and lethal syndrome. Nowadays, the Surviving Sepsis Campaign (SSC) has been developed as a guideline, but no study explores the clinical outcome.neurosurgical infection after craniotomy, mortality rate, surviving Sepsis Campaign, sepsis, Protocol
- Registration Number
- TCTR20240316003
- Lead Sponsor
- Phramongkutklao Hospital Foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 139
Inclusion Criteria
All consecutive neurosurgical patients with sepsis and septic shock admitted to the neurosurgical intensive care unit.
Exclusion Criteria
The patients that refused to study.
The patients that had pre-existing systemic disease.
The patients that were significantly limiting life expectancy.
The patients that were transferred to tertiary care hospital.
The patients that were intolerance to protocol.
The patients that were pulmonary embolism.
The patients that were congestive heart failure or acute myocardial infarction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 28-day medians survival analysis before and after the sepsis and septic shock treatment care bundle was set up 28 day 28-day medians survival analysis
- Secondary Outcome Measures
Name Time Method differences in ICU length of stay, ventilator, vasopressor-free day, and factors associated with mortality 28 day Patient reported outcome using a review sepsis and septic shock data base