The relationship between depressive symptoms and pro-inflammatory cytokine serum levels in adults with congenital heart disease

• Conditions: Congenital heart disease; 10010394; 10007510

• Registration Number: NL-OMON35960
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

Patients
- are 18 years or older
- have a congenital heart defect (excluding patients with a syndrome, such as Marfan or Noonan)
- are visiting the outpatient cardiology clinic of the AMC

Exclusion Criteria

Patients are not eligible if one or more of the following criteria apply:
- they are diagnosed with a syndrome (such as Marfan or Noonan)
- they are mentally impaired
- they are unable to independently complete a questionnaire
- they are not literate in Dutch

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The association between depressive symptoms and the serum levels of the<br /><br>pro-inflammatory cytokine TNF-* in adult CHD-patients.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The association between depressive symptoms and the serum levels of the<br /><br>pro-inflammatory cytokines IL-1 and IL-6 in adult CHD-patients.</p><br>