MedPath

Robotic Mirror Therapy System for Functional Recovery of Hemiplegic Arms

Not Applicable
Completed
Conditions
Stroke
Interventions
Device: Robotic mirror therapy
Device: Conventional mirror therapy
Registration Number
NCT02878746
Lead Sponsor
Seoul National University Hospital
Brief Summary

The investigators developed a real-time 2-axis mirror robot system as a simple add-on module for conventional mirror therapy using a closed feedback mechanism, which allows for real-time movement of the hemiplegic arm. The investigators conduct a case study for stroke patients with a two-dimensional mirror robot for 30 min per day for two weeks (10 sessions). For the conventional mirror therapy group, the investigators prepared the tasks for fine motor training.

Detailed Description

The investigators conduct a case study for stroke patients with a two-dimensional mirror robot for 30 min per day for two weeks (10 sessions). For the conventional mirror therapy group, the investigators prepared the tasks for fine motor training. These tasks included more complicated tasks so that the participants would be interested in the tasks without the robot system.

Before and after 10 sessions of the therapy, the investigators conduct functional evaluations: the Fugl-Meyer assessment scale of the upper extremity (FMA-UE), the modified Ashworth scale, the modified Barthel index of upper extremity (MBI-UE: personal hygiene, bathing, feeding, and dressing), and the Jebsen hand function test, hand power measurement, and hemispatial neglect test (line bisection test and Albert's test) with the same occupational therapist. The motor evoked potential was measured for the patients without the history of brain surgery or seizure.

The investigators selected a thumb finding test (TFT) among various tools for assessing proprioception, because TFT is widely used and reliable. The TFT can be assessed, after confirming normal proprioception in the unaffected arm, by the patient touching the nose with their eyes closed while the examiner lifts the affected arm to eye level. The patient is then asked to grasp the thumb of the affected hand with the unaffected hand, and this is repeated. The examiner then places a hand over the patient's eyes and raises the patient's affected hand to well above the patient's head. The patient is then asked to grasp the thumb as before.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
2
Inclusion Criteria
  • Over 18 years old
  • Supratentorial stroke diagnosed between 4 months and 6 years ago
  • Upper-limb hemiplegia with Medical Research Council grade 2 or less.
Exclusion Criteria
  • Severe spasticity with modified Ashworth scale of grade 3 or more;
  • Mini-mental state examination score less than 12
  • Global or sensory aphasia.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Robotic mirror therapyRobotic mirror therapyFor 30 min per day for two weeks (10 sessions)
Conventional mirror therapyConventional mirror therapyFor 30 min per day for two weeks (10 sessions)
Primary Outcome Measures
NameTimeMethod
Fugl-Meyer assessment scaleChange from baseline data at 2 weeks
Secondary Outcome Measures
NameTimeMethod
Hemispatial neglect testBefore treatment, after 2 weeks, after 2 months
Fugl-Meyer assessment scaleafter 2 months
Modified Barthel indexBefore treatment, after 2 weeks, after 2 months
Functional brain MRIBefore treatment, after 2 weeks
Thumb finding testBefore treatment, after 2 weeks, after 2 months
Modified Ashworth scaleBefore treatment, after 2 weeks, after 2 months
Hand power(lb) assessed by dynamometerBefore treatment, after 2 weeks, after 2 months
Jebsen hand function testBefore treatment, after 2 weeks, after 2 months

Trial Locations

Locations (1)

Seoul National University Hospital

🇰🇷

Seoul, Korea, Republic of

© Copyright 2025. All Rights Reserved by MedPath