Digital Mirror Therapy With Uni- and Bilateral Mirror Visual Feedback After Stroke: Treatment Effects and EEG Evidence

Not Applicable

Completed

• Conditions: Stroke; Cerebrovascular Disorders; Central Nervous System Diseases

• Registration Number: NCT04813120
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-3-21
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

Part ?: Validation of Treatment Efficacy of the New Digital MT System with Different MVF<br>Conditions and Training Modes<br><br>Inclusion Criteria:<br><br> - diagnosed with a unilateral stroke;<br><br> - at least 6 months after stroke onset;<br><br> - age between 20 and 80 years old;<br><br> - having a baseline score of Fugl-Meyer Assessment (FMA) in a range of 20 to 60;<br><br> - able to follow the study instructions;<br><br> - capable of participating in therapy and assessment sessions<br><br>Exclusion Criteria:<br><br> - global or receptive aphasia;<br><br> - severe neglect measured by line bisection test;<br><br> - other major medical diseases or comorbidities that have influenced upper-limb usage<br> or caused severe pain<br><br>Part II: Investigation of the Electrophysiological Mechanisms Underlying Different MVF<br>Conditions by EEG<br><br>Inclusion Criteria:<br><br> - diagnosed with a unilateral stroke;<br><br> - at least 2 weeks after stroke onset and medical stable;<br><br> - aged 20 to 80 years;<br><br> - having a baseline score of FMA = 40 and wrist flexion = 20 degrees in order to<br> perform EEG motor tasks;<br><br> - both wrist flexion and extension scores of Modified Ashworth Scale = 1;<br><br> - able to follow the study instructions<br><br>Exclusion Criteria:<br><br> - global or receptive aphasia;<br><br> - severe neglect measured by line bisection test;<br><br> - other major medical diseases or comorbidities, such as neurological and psychiatric<br> diseases, that have caused severe pain of upper-limb or interfered brain neural<br> activities

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change scores of Fugl-Meyer Assessment;Change scores of Chedoke Arm and Hand Activity Inventory

Secondary Outcome Measures

Name	Time	Method
change scores of Box and Block Test;change scores of Revised Nottingham Sensory Assessment;change scores of Movement Imagery Questionnaire-Revised, Second Edition;change scores of Barthel Index;change scores of Motor Activity Log;change scores of the health state of EQ-5D-5L;change scores of the visual analogue scale (VAS) of EQ-5D-5L