Phase I/II trial of carboplatin, TS-1, and concurrent radiation therapy in patients with unresectable locally advanced non-small cell lung cancer - Phase I/II trial of carboplatin, TS-1, and concurrent radiation therapy in patients with unresectable locally advanced non-small cell lung cancer

Dokkyo Medical University0 个研究点目标入组 40 人开始时间: 2013年9月5日最近更新: 2023年10月17日

适应症

试验速览

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•1)Patients with interstitial pneumonia or pulmonary fibrosis on Chest X-ray 2)Patients with pleural or pericardial effusion ,or ascites 3) Patients with active double cancer 4)Patients with significant complications a) Uncontrolled angina pectoris, myocardial infarction, heart failure within 3 months b)Uncontrolled diabetes or hypertension c)Current severe infection, or suspicious of severe infection d) Patients whose participation in the trial is judged to be inappropriate by the attending doctor. (e.g., ileus, bleeding tendency, diarrhea and varicella) 5)Patients with symptomatic brain metastasis 6)Patients with pregnancy or lactation 7) History of serious allergic reaction with CBDCA or other platinum-containing drug 8) History of serious allergic reaction with S-1 9) Being treated with other pyrimidine fluoride antineoplastic agents. 10) Being treated with flucytosine. 11) Any patients judged by the investigator to be unfit to participate in the study

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