Phase I/II trial of carboplatin plus CPT-11 chemotherapy with accelerated hyperfractionated radiotherapy for elderly patients with limited stage small cell lung cancer (TORG0604).
Phase 1
- Conditions
- limited stage small cell lung cancer
- Registration Number
- JPRN-UMIN000007352
- Lead Sponsor
- Thoracic Oncology Research Group (TORG)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 41
Inclusion Criteria
Not provided
Exclusion Criteria
1) other active malignancy 2) active infection 3) obviously proven interstitial lund disease by x-ray 4) myocardiac infarction within six monthes before registration 5) uncontrollable heart diseases or hepatic diseeases or diabates or hemorrhage 6) severe mental disorder 7) diarrhea or watery stool 8) massive pleural effusion (more than one centimeter thickness of chest CT scan) 9) ileus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Phase I: recommended dose Phase II:toxicity profiles, response rate, feasibility
- Secondary Outcome Measures
Name Time Method overall survival progression free survival