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Carbetocin versus Oxytocin for the Prevention of Postpartum Hemorrhage in Hypertensive Pregnant Women

faculty of medicine suez canal university0 个研究点目标入组 160 人开始时间: 2019年8月23日最近更新:

试验速览

阶段
未知
状态
已完成
入组人数
160

研究概览

简要总结

Both drugs were associated with a statistically significant decrease in blood pressure. Hemoglobin decreased significantly among the oxytocin group (pre-operative hemoglobin 12.1 ± 3.8 versus post-operative 10.4 ± 1.1). Blood loss was significantly more among the oxytocin group (424.75 ± 182.59 in carbetocin group versus 679.5 ± 200.25 in the oxytocin group, p- value <0.001). Nausea, vomiting, and sweating were reported more significantly in oxytocin group patients.

研究设计

研究类型
Interventional

入排标准

年龄范围
19 Year(s) 至 44 Year(s)(—)
性别
Female

入选标准

  • women aged 18-35 years
  • with term singleton pregnancy
  • prepared for elective lower segment CS at gestational age of = 37 weeks wit
  • h diagnosed hypertensive disorders in pregnancy.

排除标准

  • risk factors for excessive blood loss during the surgery (placenta previa,
  • twin pregnancy or presence of uterine fibroid),
  • a history of thromboembolic disorders
  • cases suffering from chronic medical diseases (cardiac, hepatic, renal).

研究者

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