Conventional open versus laparoscopic surgery for peritoneal dialysis (PD) peritonitis

Completed

• Conditions: Peritoneal dialysis (PD) peritonitis; Digestive System; Peritonitis

• Registration Number: ISRCTN55802603
• Lead Sponsor: niversity Hospitals of Leicester NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-11-30
• Last Update Posted: 30 October 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Any patient (both males and females) 18 years or over presenting with PD peritonitis requiring surgery referred by a nephrologist to the surgical team as defined below:
1.1. Failure of the medical treatment described above i.e. refractory peritonitis. In these cases the use of appropriate IP/IVantibiotics fails to improve the patient's clinical condition (pain and abdominal tenderness) and the turbid effluent PD fluid doesn't become clear, suggesting that infection is ongoing. There may also be signs of systemic sepsis with persistent tachycardia, pyrexia, a raised white count and a raised C reactive protein
1.2. Clinical signs of generalised peritonitis: generalised severe abdominal tenderness with rigidity, rebound tenderness and loss of bowel sounds
1.3. Peritonitis caused by pseudomonas species
1.4. Fungal peritonitis
2. The above patients that are not already included in a clinical trial
3. The above patients that consent to participate in the trial

Exclusion Criteria

1. Patients from which formal consent cannot be taken
2. Patients with poor respiratory function that may be put at risk by laparoscopic surgery as assessed by an anaesthetist
3. Patients that have had multiple laparotomy procedures and history of adhesions as a result of the surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified