Comparison Of Postoperative Pain Relief Following Intraperitoneal Deposition Of Levobupivacaine With And Without Dexmedetomedine In Laparoscopic Cholecystectomy

Phase 3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2025/05/087082
• Lead Sponsor: Vinayaka Missions Medical College and Hospital

Brief Summary

**INTRODUCTION**Laparoscopicprocedures has many advantages over open procedures, such as lesser hemorrhage,better cosmetic results, lesser post-operative pain, and shorter recovery time,leading to shorter hospital stay and less expenditure.

Postoperative pain is reduced compared to the open surgery, buteffective analgesic treatment after laparoscopic cholecystectomy has remained aclinical challenge.

Local anesthetic instillation in the peritoneal cavity decreasesintensity of postoperative pain after laparoscopic surgeries.

**INNOVATIVE CONCEPT OF THE PROJECT**

Local anaesthetics has been used for control of painby intra peritoneal instillation and has become an important addition forpostoperative pain in the era of modern surgery. The role and dosing ofLevobupivacaine and dexmeditomidine is relatively new.

**AIM**



Tocompare the duration of post operative analgesia offered by intraperitonealLevobupivacaine alone or with dexmedetomidine in patients undergoinglaparoscopic cholecystectomy.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-05-16
• Study Start: 2025-05-27

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

ASA I and II Patient undergoing laparoscopic cholecystectomy.

Exclusion Criteria

1.ASA III & IV 2.History of allergy to study drug 3.Patients in whom abdominal drain is in-situ 4.Patients who are unable to express VAS score accurately(mentally ill patients) 5.Patient refusal.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the duration of post operative analgesia offered by intraperitoneal Levobupivacaine alone or with dexmedetomidine in patients undergoing laparoscopic cholecystectomy and subsequent need of rescue analgesic	until first rescue analgesia

Secondary Outcome Measures

Name	Time	Method
Total rescue analgesic consumption and Post-operative adverse effects

Trial Locations

Locations (1)

Vinayaka Missions Medical College and Hospital; 🇮🇳 Karaikal, PONDICHERRY, India

Vinayaka Missions Medical College and Hospital

🇮🇳Karaikal, PONDICHERRY, India

Dr Suba L

Principal investigator

9578567506

suba.cutiepie@gmail.com