Evaluation of the effect of licorice as an adjunctive therapy for patients with Covid-19 admitted to the intensive care unit
Phase 3
Recruiting
- Conditions
- Covid-19.U07.1U07.1 COVID-19, virus identified
- Registration Number
- IRCT20081208001497N10
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Covid-19 diagnosis based on PCR test
Hospitalized in the intensive care unit and under mechanical ventilation
Exclusion Criteria
1. Patients with high blood pressure (<90/140)
Patients with congestive heart failure
Patients with severe liver, kidney and thyroid disease
Concomitant use of warfarin, SSRI, MAOI, diuretics, antiarrhythmic drugs
Treatment with antiviral drugs one month before entering the study
Allergy to licorice
Pregnancy and lactation
Dissatisfaction of the patient or his legal guardian
Infected with Covid-19 for at least 20 days prior to enrollment
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Average time out of intensive care unit. Timepoint: After discharge. Method of measurement: Number of hospitalization days.
- Secondary Outcome Measures
Name Time Method Speed of recovery of Covid-19 clinical signs. Timepoint: The first and fourteenth day. Method of measurement: Percentage of improvement in symptoms.;Duration of hospitalization in the intensive care unit. Timepoint: After discharge or death. Method of measurement: Number of days of hospitalization.;Duration of mechanical ventilation. Timepoint: During hospitalization. Method of measurement: Number of days under mechanical ventilation.