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The effect of licorice administration on patients with rheumatoid arthritis

Phase 2
Recruiting
Conditions
Rheumatoid Arthritis.
Rheumatoid arthritis with rheumatoid factor
Registration Number
IRCT20221127056629N1
Lead Sponsor
sirjan school of medical science
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
76
Inclusion Criteria

Patients with joint rheumatism referring to Sirjan Faculty of Medical Sciences clinic
Filling the consent form by patients

Exclusion Criteria

Heart, kidney or hypertension patients, history of heart attack, high blood lipids, abnormal kidney or liver function, use of non-steroidal anti-inflammatory drugs, use of vitamins and/or mineral supplements and drugs such as thyroid hormones, anti-hypertensive drugs Blood, contraceptives, diuretics and beta-blockers, as well as alcohol consumption, smoking, pregnancy and breastfeeding
Other underlying diseases and also it should be mentioned that each person participating in the study will be excluded from the study in case of discontinuation of treatment or side effects caused by the consumption of licorice.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Disease severity. Timepoint: 0?90. Method of measurement: Disease activity score 28 ( DAS28).
Secondary Outcome Measures
NameTimeMethod
Erythrocyte sed?mentation rate. Timepoint: 0?90. Method of measurement: Westergren method.;Intensity of pain. Timepoint: 0?90. Method of measurement: The patients will be asked to mark their pain level from their point of view on a ten-point scale.;CRP. Timepoint: 0,90. Method of measurement: Agglutination method.;TNF-a. Timepoint: 0,90. Method of measurement: Eliza method.;IL-6. Timepoint: 0,90. Method of measurement: Eliza method.;Systolic blood pressure. Timepoint: 0,90. Method of measurement: by barometer.;Diastolic blood pressure. Timepoint: 0,90. Method of measurement: by barometer.;AST. Timepoint: 0,90. Method of measurement: Colorimetric method and photometer.;Licorice. Timepoint: 0,90. Method of measurement: by scales.;Potassium. Timepoint: 0,90. Method of measurement: Flynn photometry method.;Fasting blood sugar. Timepoint: 0?90. Method of measurement: Colorimetric method and photometer.
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