Pragmatic randomized controlled multi center trial comparing the effectiveness of antibacterial therapeutic clothing based on silver or chitosan as compared with non-antibacterial therapeutic clothing in patients with moderate to severe atopic dermatitis (AD)
Completed
- Conditions
- Atopic dermatitiseczema10014982
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 165
Inclusion Criteria
- AD diagnosed according to the criteria of Williams (Williams 1994);
- Age: 0 - 80 years;
- AD severity according to EASI at t <= 0: > 6.0
Exclusion Criteria
- Treatment with oral antibiotics until 1 month before inclusion;
- Treatment with topical antibiotics until 1 week before inclusion;
- Treatment with systemic immunosuppressive agents or light therapy until 1
month before inclusion;
- Treatment with (antibacterial) therapeutic clothing until 1 month before
inclusion;
- Impaired kidney function (anamnestic assessed)
- Pregnancy or pregnancy wish during study (anamnestic assessed)
- Hypersensitivity to silver (anamnestic assessed)
- Evidence of past non-compliance to treatments or appointments.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To assess the effectiveness of antibacterial clothing based on silver or<br /><br>chitosan on the doctor-reported AD severity (Eczema Area and Severity Index,<br /><br>EASI) in patients with moderate to severe AD.</p><br>
- Secondary Outcome Measures
Name Time Method