A randomized comparative study to evaluate the analgesic effect of intravenous versus perineural dexmedetomidine as an adjuvant to bupivacaine in ultrasound-guided adductor canal block in patients undergoing total knee arthroplasty.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- no significant difference in onset of sensory block between IV and perineural administration of dexmedetomidine as an adjuvant to bupivacaine in USG guided adductor canal block in patients undergoing total knee arthroplasty.
Study Overview
Brief Summary
The purpose of study is to compare which route between IV and perineural administration of Dexmedetomidine as an adjuvant to bupivacaine in USG guided adductor canal block is better for the onset of sensory block and analgesic effect.
We are doing this study because Total Knee Arthroplasty is associated with severe post operative pain and Adductor Canal Block is primarily a sensory block. Dexmedetomidine is a highly selective alpha-2 adrenergic agonist that is effectively used as a safe analgesic adjuvant. By finding which route (IV vs Perineural ) is better we can use dexmedetomidine as an adjuvant by that route safely.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 90.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Undergoing total knee replacement Informed written conscent American society of anesthesiologists grade 1,2 and 3.
Exclusion Criteria
- •Psychiatric illness Peripheral sensorineural deficit Allergic to study drugs Infection at site of block Compartment syndrome.
Outcomes
Primary Outcomes
no significant difference in onset of sensory block between IV and perineural administration of dexmedetomidine as an adjuvant to bupivacaine in USG guided adductor canal block in patients undergoing total knee arthroplasty.
Time Frame: 5min ,10mins,15 mins,20 mins postoperative
Secondary Outcomes
No secondary outcomes reported
Investigators
Dr Harsimrat Kaur
Sawai Maan Singh Medical college