A randomized comparative study to evaluate the analgesic effect of intravenous versus perineural dexmedetomidine as an adjuvant to bupivacaine in ultrasound-guided adductor canal block in patients undergoing total knee arthroplasty.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- no significant difference in onset of sensory block between IV and perineural administration of dexmedetomidine as an adjuvant to bupivacaine in USG guided adductor canal block in patients undergoing total knee arthroplasty.
研究概览
简要总结
The purpose of study is to compare which route between IV and perineural administration of Dexmedetomidine as an adjuvant to bupivacaine in USG guided adductor canal block is better for the onset of sensory block and analgesic effect.
We are doing this study because Total Knee Arthroplasty is associated with severe post operative pain and Adductor Canal Block is primarily a sensory block. Dexmedetomidine is a highly selective alpha-2 adrenergic agonist that is effectively used as a safe analgesic adjuvant. By finding which route (IV vs Perineural ) is better we can use dexmedetomidine as an adjuvant by that route safely.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Undergoing total knee replacement Informed written conscent American society of anesthesiologists grade 1,2 and 3.
排除标准
- •Psychiatric illness Peripheral sensorineural deficit Allergic to study drugs Infection at site of block Compartment syndrome.
结局指标
主要结局
no significant difference in onset of sensory block between IV and perineural administration of dexmedetomidine as an adjuvant to bupivacaine in USG guided adductor canal block in patients undergoing total knee arthroplasty.
时间窗: 5min ,10mins,15 mins,20 mins postoperative
次要结局
未报告次要终点
研究者
Dr Harsimrat Kaur
Sawai Maan Singh Medical college