ltra-high field fMRI of subcortical auditory structures in patients with tinnitus - Ultrahigh field fMRI in tinnitus

Clinical Trail Center Maastricht0 sites14 target enrollmentTBD

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

March 13, 2015

Last Updated

2 years ago

Study Type

Observational non invasive

Sponsor

Clinical Trail Center Maastricht

•The main inclusion criteria of the tinnitus group are unilateral (i.e. tinnitus is experienced at one side of the head/at one ear), chronic (i.e. longer present than 6 months) and subjective (not caused by an acoustic source inside the head) tinnitus. Age between 18 and 75 years and a written informed consent prior to study initiation.

•Exclusion criteria are: Fletcher Index \> 50 dB HL for both ears (i.e. mean of hearing loss in decibels for 1 kHz, 2 kHz en 4 kHz), difference in average hearing threshold of more than 10 dB between left and right ear (large differences will influence the intra\-individual analysis), hyperacusis (i.e. oversensitivity of sound), phonophobia (i.e. a persistent, abnormal and unwarranted fear of sound), misophonia (i.e. dislike of certain sounds), neurological\-, neurosurgical\- and psychiatric history, use of dopaminergic drugs (since this medication greatly influence the fMRI scans), morbid obesitas (BMI \> 35\) since it cannot be guaranteed that these subjects will fit in the scanner, current treatment of tinnitus and implanted devices or other metal objects that are not suitable for MRI.