NL-OMON41696
Completed
Not Applicable
ltra-high field imaging of the cortico-striato-subthalamic functional and structural connectivity to improve deep brain stimulation surgery in Parkinson's disease patients - STN connectivity in PD with MRI
Medisch Universitair Ziekenhuis Maastricht0 sites45 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson's
- Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Enrollment
- 45
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •For all groups:
- •1\. Subjects must be mentally competent;For group 1 (PD patients scheduled for DBS surgery):
- •1\. Patients suffering from Parkinson's disease who are eligible for deep brain stimulation surgery.;For group 2 (PD patients not scheduled for DBS surgery):
- •1\. Diagnosis of idiopathic PD according to the UK Brain Bank Criteria
- •2\. Excellent levodopa response
- •3\. Disease course of \> 3 years;For the healthy controls only:
- •1\. Healthy volunteers with the same age and gender distribution as both patient populations.
Exclusion Criteria
- •For all groups:
- •1\. Metallic prostheses or pacemaker in the subject's body or other contra indications for MRI.
- •2\. Any neurological disease (other than PD).;For group 1 (PD patients scheduled for DBS surgery):
- •1\. Any neurological or psychiatric disease other than PD.;For group 2 (PD patients not scheduled for DBS surgery)
- •1\. Any neurological or psychiatric disease other than PD.;For healthy volunteers:
- •1\. Any neurological or psychiatric disease.
- •2\. The use of medication affecting the central nervous system.
Outcomes
Primary Outcomes
Not specified
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