ltra-high field imaging of the cortico-striato-subthalamic functional and structural connectivity to improve deep brain stimulation surgery in Parkinson's disease patients - STN connectivity in PD with MRI

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 45 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•For all groups:
•1. Subjects must be mentally competent;For group 1 (PD patients scheduled for DBS surgery):
•1. Patients suffering from Parkinson's disease who are eligible for deep brain stimulation surgery.;For group 2 (PD patients not scheduled for DBS surgery):
•1. Diagnosis of idiopathic PD according to the UK Brain Bank Criteria
•2. Excellent levodopa response
•3. Disease course of > 3 years;For the healthy controls only:
•1. Healthy volunteers with the same age and gender distribution as both patient populations.

•For all groups:
•1. Metallic prostheses or pacemaker in the subject's body or other contra indications for MRI.
•2. Any neurological disease (other than PD).;For group 1 (PD patients scheduled for DBS surgery):
•1. Any neurological or psychiatric disease other than PD.;For group 2 (PD patients not scheduled for DBS surgery)
•1. Any neurological or psychiatric disease other than PD.;For healthy volunteers:
•1. Any neurological or psychiatric disease.
•2. The use of medication affecting the central nervous system.

发起方

Medisch Universitair Ziekenhuis Maastricht