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Clinical Trials/NCT03122067
NCT03122067
Unknown
Not Applicable

Oxytocinergic Modulation of Perceived Social Exclusion

University of Electronic Science and Technology of China1 site in 1 country60 target enrollmentJanuary 10, 2017

Overview

Phase
Not Applicable
Intervention
placebo treatment
Conditions
Healthy
Sponsor
University of Electronic Science and Technology of China
Enrollment
60
Locations
1
Primary Endpoint
Neural activity changes associated with oxytocin administration
Last Updated
8 years ago

Overview

Brief Summary

The aim of the present experiment is to examine oxytocin's behavioral and neural effects on social pain empathy

Detailed Description

In the current study, the investigators plan to examine whether oxytocin modulates behavior and neural activity during observing another person being excluded in an online ball-tossing game (a modified cyberball paradigm).

Registry
clinicaltrials.gov
Start Date
January 10, 2017
End Date
October 30, 2018
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Sponsor
University of Electronic Science and Technology of China
Responsible Party
Principal Investigator
Principal Investigator

Keith Kendrick

Professor

University of Electronic Science and Technology of China

Eligibility Criteria

Inclusion Criteria

  • healthy participants without past or current psychiatric or neurological disorders

Exclusion Criteria

  • history of head injury
  • medical or psychiatric illness
  • smoking or drinking 24 hours before experiment

Arms & Interventions

placebo group

male participants with placebo treatment

Intervention: placebo treatment

oxytocin group

male participants with oxytocin treatment

Intervention: oxytocin treatment

Outcomes

Primary Outcomes

Neural activity changes associated with oxytocin administration

Time Frame: 45-60 minutes after drug administration

fMRI-assessed brain activity during observing other being socially excluded

Secondary Outcomes

  • Behavioral changes associated with oxytocin administration: ball-tossing(45-60 minutes after drug administration)

Study Sites (1)

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