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临床试验/NCT03122067
NCT03122067Unknown不适用

Oxytocinergic Modulation of Perceived Social Exclusion

University of Electronic Science and Technology of China1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2017年1月10日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
发起方
入组人数
60
试验地点
1
主要终点
Neural activity changes associated with oxytocin administration

研究概览

简要总结

The aim of the present experiment is to examine oxytocin's behavioral and neural effects on social pain empathy

详细描述

In the current study, the investigators plan to examine whether oxytocin modulates behavior and neural activity during observing another person being excluded in an online ball-tossing game (a modified cyberball paradigm).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • healthy participants without past or current psychiatric or neurological disorders

排除标准

  • history of head injury
  • medical or psychiatric illness
  • smoking or drinking 24 hours before experiment

研究组 & 干预措施

placebo group

Placebo Comparator

male participants with placebo treatment

干预措施: placebo treatment (Drug)

oxytocin group

Experimental

male participants with oxytocin treatment

干预措施: oxytocin treatment (Drug)

结局指标

主要结局

Neural activity changes associated with oxytocin administration

时间窗: 45-60 minutes after drug administration

fMRI-assessed brain activity during observing other being socially excluded

次要结局

  • Behavioral changes associated with oxytocin administration: ball-tossing(45-60 minutes after drug administration)

研究者

发起方
University of Electronic Science and Technology of China
申办方类型
Other
责任方
Principal Investigator
主要研究者

Keith Kendrick

Professor

University of Electronic Science and Technology of China

研究点 (1)

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