Oxytocinergic Modulation of Perceived Social Exclusion
Overview
- Phase
- Not Applicable
- Intervention
- placebo treatment
- Conditions
- Healthy
- Sponsor
- University of Electronic Science and Technology of China
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Neural activity changes associated with oxytocin administration
- Last Updated
- 8 years ago
Overview
Brief Summary
The aim of the present experiment is to examine oxytocin's behavioral and neural effects on social pain empathy
Detailed Description
In the current study, the investigators plan to examine whether oxytocin modulates behavior and neural activity during observing another person being excluded in an online ball-tossing game (a modified cyberball paradigm).
Investigators
Keith Kendrick
Professor
University of Electronic Science and Technology of China
Eligibility Criteria
Inclusion Criteria
- •healthy participants without past or current psychiatric or neurological disorders
Exclusion Criteria
- •history of head injury
- •medical or psychiatric illness
- •smoking or drinking 24 hours before experiment
Arms & Interventions
placebo group
male participants with placebo treatment
Intervention: placebo treatment
oxytocin group
male participants with oxytocin treatment
Intervention: oxytocin treatment
Outcomes
Primary Outcomes
Neural activity changes associated with oxytocin administration
Time Frame: 45-60 minutes after drug administration
fMRI-assessed brain activity during observing other being socially excluded
Secondary Outcomes
- Behavioral changes associated with oxytocin administration: ball-tossing(45-60 minutes after drug administration)