ASSESSMENT OF SOFT TISSUE HEALING OVER IMMEDIATELY PLACED IMPLANT SEALED WITH PLATELETS RICH FIBRIN (PRF) VERSUS DIODE LASER

Not Applicable

Completed

• Conditions: Immediate Implant Soft Tissue Healing
• Interventions: Device: Diode laser; Biological: Platelet Rich Fibrin

• Registration Number: NCT05517733
• Lead Sponsor: Nourhan M.Aly

Brief Summary

Aim of the current study was to assess the efficacy of PRF in comparison to diode laser to promote tissue healing and soft tissue quality after placement of immediate implants.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-10
• Primary Completion: 2022-06-20
• Study Completion: 2022-06-30
• Status Verified: 2022-08
• Study First Submitted: 2022-08-24
• Study First Submitted QC: 2022-08-24
• Last Update Submitted: 2022-08-24
• Study First Posted: 2022-08-26
• Last Update Posted: 2022-08-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Any non-restorable hopeless tooth: a badly decayed tooth that cannot be restored, tooth with failed endodontic treatment, and teeth with longitudinal fracture.
• Post-extraction sockets type 1 with all bony walls intact; Type I extraction sockets according to Elian classification in 2007 have an intact labial plate of the bone and no soft tissue recession. Therefore, it does not require a mucoperiosteal flap elevation, only bone graft particles are packed into the socket after atraumatic extraction and socket debridement, then sealed with barrier membranes or soft tissue grafts.
• No signs of active periodontal disease in the selected tooth.
• Good oral hygiene

Exclusion Criteria

• The presence of any systemic disease could complicate bone or soft tissue healing after immediate implant placement.
• The presence of Acute periapical infection.
• The presence of any local factor that may interfere with extraction as tooth ankyloses
• Subjects who had undergone therapeutical radiation. (187)
• Patients who had been subjected to or who were under bisphosphonate therapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Diode laser	Diode laser	-
Platelet Rich Fibrin (PRF)	Platelet Rich Fibrin	-

Primary Outcome Measures

Name	Time	Method
Mid-buccal soft tissue thickness	up to 8 weeks	Measured from the gingival margin to implant platform using a periodontal probe.
Mid-crestal soft tissue height	up to 8 weeks	Measured using a periodontal probe passing through soft tissue in the intersection midpoint of both buccolingual and mesiodistal dimensions of the socket till cover screw.
Soft tissue healing	up to 4 weeks	This was done using Landry healing index. It evaluates the parameters of tissue colour, bleeding response to palpation, presence of granulation tissue, characteristics of the incision margins, and the presence of suppuration. The score ranges from 1 (Very poor) to 5 (Excellent).

Secondary Outcome Measures

Name	Time	Method
Post-operative pain level	24 hours	This was measured using the Visual Analogue Scale (VAS) that rates pain level on a scale of 0-10 (with 0 meaning no pain at all and 100 meaning the worst possible pain). A VAS questionnaire was given to the subjects and they were asked to select their pain score.

Trial Locations

Locations (1)

Faculty of Dentistry, Alexandria University; 🇪🇬 Alexandria, Egypt