A New Approach to a Personalized Patient Blood Management Program in Total Hip Arthroplasty
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 477
- 试验地点
- 1
- 主要终点
- Events and circumstances of Homologous Blood Transfusion (erythrocyte concentrate transfusion)
研究概览
简要总结
The study evaluates the patient related risk and predictive factors concerning perioperative homologous blood cell transfusion (erythrocyte concentrate ) in THA patients in one EndoCert max-certified orthopedic hospital in Germany.
A patient oriented preoperative decision-making algorithm (a personalised Patient Blood Management or pPBM App) will be developed as a new patient-safety blood-sparing strategy.
The aim is to increase the patient safety by using the pPBM App and to reach a more efficient management of resources.
详细描述
Retrospective audit of 470 consecutive primary THA in 2013 and 2014
研究设计
- 研究类型
- Observational
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •primary THA on patients with coxarthrosis
排除标准
- •any kind of old or acute fractures about the basin and hip
- •combined surgery, like first extracting a femur nail and than undergoing THA
- •any other kind of combined or simultaneous surgery
- •any kind of coagulopathy
结局指标
主要结局
Events and circumstances of Homologous Blood Transfusion (erythrocyte concentrate transfusion)
时间窗: participants will be followed for the duration of hospital stay, an expected average of 10 days
Multivariate analysis of predictive variables like age, sex, BMI, hip and belly circumference, chronic kidney disease, chronic cardio-vascular disease, chronic inflammatory disease, diabetes mellitus, cancer, ASA Score, cemented, hybrid or not cemented prosthesis, surgery duration, medication and hemoglobin level before surgery
次要结局
- pPBM Computer Simulation(participants will be followed for the duration of hospital stay, an expected average of 10 days)
研究者
Ion-Andrei Popescu, MD
Ion-Andrei Popescu, MD
Krankenhaus der Barmherzigen Brüder Trier