Hyperplastic polyposis syndrome: Endoscopic treatment and surveillance.
Recruiting
- Conditions
- hyperplastic polyposis CRC serrated adenoma HPSB colorectal carcinoma HPS
- Registration Number
- NL-OMON27090
- Lead Sponsor
- Academic Medical Centre (AMC)
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 125
Inclusion Criteria
HPS patients defined as:
> 5 HPs/SSA proximal to the sigmoid, of which 2 > 10 mm in diameter, or more than 20 HPs/SSAs distributed throughout the colon.
Exclusion Criteria
Carriers of a germline mutation in the MutYH or APC gene and individuals who have undergone a total colonic resection.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.
- Secondary Outcome Measures
Name Time Method The incidence of complications: The amount of polypectomies and the rate of protcol deviations and conversions to surgical resection will be assessed.