External-Beam Radiation Therapy Plus Implanted Radiation Therapy in Treating Patients With Prostate Cancer
- Conditions
- Prostate Cancer
- Interventions
- Radiation: brachytherapyRadiation: iodine I 125Radiation: radiation therapy
- Registration Number
- NCT00006365
- Lead Sponsor
- Radiation Therapy Oncology Group
- Brief Summary
RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Giving radiation therapy in different ways may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of external-beam radiation therapy followed by implanted radiation therapy in treating patients who have prostate cancer.
- Detailed Description
OBJECTIVES: I. Determine the acute and late grade 3-5 genitourinary (GU) and gastrointestinal (GI) toxic effects of external beam radiotherapy followed by permanent source brachytherapy using interstitial iodine I 125 seeds in patients with intermediate risk, clinically localized adenocarcinoma of the prostate. II. Determine the freedom from prostate specific antigen (PSA) failure, overall survival, disease specific survival, and local and/or distant clinical relapse rates in patients treated with this regimen.
OUTLINE: This is a multicenter study. Patients undergo external beam radiotherapy (EBRT) to the pelvis 5 days a week for 5 weeks. Permanent source brachytherapy comprised of ultrasound-guided implantation of iodine I 125 seeds into the prostate is performed 2-6 weeks after completion of EBRT. Patients are followed at 1, 3, 6, 9, and 12 months, then every 6 months for 2 years, and then annually thereafter.
PROJECTED ACCRUAL: A total of 110 patients will be accrued for this study within 1 year.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 138
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description EBRT to the prostate followed by brachytherapy radiation therapy Patients received 45 Gy of external beam radiation therapy (EBRT)to the prostate followed (within 2 to 6 weeks) by permanent iodine (I-125) brachytherapy 108 Gy. EBRT to the prostate followed by brachytherapy iodine I 125 Patients received 45 Gy of external beam radiation therapy (EBRT)to the prostate followed (within 2 to 6 weeks) by permanent iodine (I-125) brachytherapy 108 Gy. EBRT to the prostate followed by brachytherapy brachytherapy Patients received 45 Gy of external beam radiation therapy (EBRT)to the prostate followed (within 2 to 6 weeks) by permanent iodine (I-125) brachytherapy 108 Gy.
- Primary Outcome Measures
Name Time Method Rate of late severe GU and GI toxicity Start of radiotherapy to at least 18 months of follow-up Rate of late severe GU and GI toxicity defined as grade 3-5 GU and GI toxicity based on Common Toxicity Criteria 2.0
- Secondary Outcome Measures
Name Time Method Overall failure From the date of study entry to the date of death due to any cause Rate of acute severe GU and GI toxicity Nine months from the start of radiotherapy Rate of acute severe GU and GI toxicity, defined as grde 3-5 GU and GI toxicity based on Common Toxicity Criteria 2.0
Biochemical Failure From the date of study entry to the date of first occurrence of PSA failure once by ASTRO definition of 3 years of follow-up been completed for all patients Failure rate of clinical progression including local-regional/distant failure Documented evidence of local progression or regional nodal recurrence or distant disease relapse
Trial Locations
- Locations (254)
CCOP - Columbus
🇺🇸Columbus, Ohio, United States
Arthur G. James Cancer Hospital - Ohio State University
🇺🇸Columbus, Ohio, United States
Hahnemann University Hospital
🇺🇸Philadelphia, Pennsylvania, United States
University of Pennsylvania Cancer Center
🇺🇸Philadelphia, Pennsylvania, United States
Albert Einstein Cancer Center
🇺🇸Philadelphia, Pennsylvania, United States
CCOP - Atlanta Regional
🇺🇸Atlanta, Georgia, United States
Harbor Hospital Center
🇺🇸Baltimore, Maryland, United States
Sinai Hospital of Baltimore
🇺🇸Baltimore, Maryland, United States
Radiation Oncology Affiliates of Maryland, P.A.
🇺🇸Baltimore, Maryland, United States
Virginia Mason Medical Center
🇺🇸Seattle, Washington, United States
Baptist Hospital of Miami
🇺🇸Miami, Florida, United States
Veterans Affairs Medical Center - Indianapolis (Roudebush)
🇺🇸Indianapolis, Indiana, United States
Clarion Health Partners Inc.
🇺🇸Indianapolis, Indiana, United States
Barrett Cancer Center, The University Hospital
🇺🇸Cincinnati, Ohio, United States
Vanderbilt-Ingram Cancer Center
🇺🇸Nashville, Tennessee, United States
University of Utah Health Sciences Center
🇺🇸Salt Lake City, Utah, United States
Newark Beth Israel Medical Center
🇺🇸Newark, New Jersey, United States
South Jersey Regional Cancer Center
🇺🇸Millville, New Jersey, United States
Norris Cotton Cancer Center
🇺🇸Lebanon, New Hampshire, United States
CCOP - Montana Cancer Consortium
🇺🇸Billings, Montana, United States
Veterans Affairs Medical Center - East Orange
🇺🇸East Orange, New Jersey, United States
John F. Kennedy Medical Center
🇺🇸Edison, New Jersey, United States
Nova Scotia Cancer Centre
🇨🇦Halifax, Nova Scotia, Canada
Tom Baker Cancer Center - Calgary
🇨🇦Calgary, Alberta, Canada
CCOP - Southern Nevada Cancer Research Foundation
🇺🇸Las Vegas, Nevada, United States
Elliot Regional Cancer Center
🇺🇸Manchester, New Hampshire, United States
Huntsville Hospital System
🇺🇸Huntsville, Alabama, United States
MBCCOP - Gulf Coast
🇺🇸Mobile, Alabama, United States
Comprehensive Cancer Institute of Huntsville
🇺🇸Huntsville, Alabama, United States
Providence Alaska Medical Center
🇺🇸Anchorage, Alaska, United States
Radiation Oncology Associates of West Alabama
🇺🇸Tuscaloosa, Alabama, United States
Loma Linda University Medical Center
🇺🇸Loma Linda, California, United States
Arizona Cancer Center
🇺🇸Tucson, Arizona, United States
Saint Agnes Cancer Center
🇺🇸Fresno, California, United States
Mount Diablo Medical Center
🇺🇸Concord, California, United States
California Cancer Center
🇺🇸Fresno, California, United States
Glendale Memorial Hospital and Health Center
🇺🇸Glendale, California, United States
Sutter Health West Cancer Research Group
🇺🇸Greenbrae, California, United States
USC/Norris Comprehensive Cancer Center and Hospital
🇺🇸Los Angeles, California, United States
Veterans Affairs Medical Center - Long Beach
🇺🇸Long Beach, California, United States
Huntington Cancer Center
🇺🇸Pasadena, California, United States
Radiation Medical Group, Inc.
🇺🇸San Diego, California, United States
UCSF Cancer Center and Cancer Research Institute
🇺🇸San Francisco, California, United States
O'Connor Hospital
🇺🇸San Jose, California, United States
CCOP - Santa Rosa Memorial Hospital
🇺🇸Santa Rosa, California, United States
Memorial Hospital Cancer Center
🇺🇸Colorado Springs, Colorado, United States
CCOP - Christiana Care Health Services
🇺🇸Wilmington, Delaware, United States
Saint Mary's Hospital and Medical Center
🇺🇸Grand Junction, Colorado, United States
Veterans Affairs Medical Center - Miami
🇺🇸Miami, Florida, United States
Sylvester Cancer Center, University of Miami
🇺🇸Miami, Florida, United States
Walter Reed Army Medical Center
🇺🇸Washington, District of Columbia, United States
Lykes Center for Radiation Therapy
🇺🇸Clearwater, Florida, United States
Northwestern Memorial Hospital
🇺🇸Chicago, Illinois, United States
Radiation Therapy Associates - Fort Myers
🇺🇸Fort Myers, Florida, United States
Health First Holmes Regional Medical Center
🇺🇸Melbourne, Florida, United States
Emory University Hospital - Atlanta
🇺🇸Atlanta, Georgia, United States
Florida Radiation Oncology Group
🇺🇸Orange Park, Florida, United States
CCOP - Central Illinois
🇺🇸Decatur, Illinois, United States
Northwest Community Hospital
🇺🇸Arlington Heights, Illinois, United States
University of Chicago Cancer Research Center
🇺🇸Chicago, Illinois, United States
Ingalls Memorial Hospital
🇺🇸Harvey, Illinois, United States
Provena St. Joseph Hospital- Regional Cancer Care Center
🇺🇸Elgin, Illinois, United States
Lutheran General Cancer Care Center
🇺🇸Park Ridge, Illinois, United States
Methodist Medical Center of Illinois
🇺🇸Peoria, Illinois, United States
Ball Memorial Hospital
🇺🇸Muncie, Indiana, United States
Wendt Regional Cancer Center of Finley Hospital
🇺🇸Dubuque, Iowa, United States
St. John's Medical Center
🇺🇸Anderson, Indiana, United States
Romagosa Radiation Oncology Center
🇺🇸Lafayette, Louisiana, United States
Bloomington Hospital
🇺🇸Bloomington, Indiana, United States
Community Hospitals of Indianapolis - Regional Cancer Center
🇺🇸Indianapolis, Indiana, United States
Veterans Affairs Medical Center - Lexington
🇺🇸Lexington, Kentucky, United States
Mary Bird Perkins Cancer Center
🇺🇸Baton Rouge, Louisiana, United States
Albert B. Chandler Medical Center, University of Kentucky
🇺🇸Lexington, Kentucky, United States
CCOP - Ochsner
🇺🇸New Orleans, Louisiana, United States
Maine Medical Center
🇺🇸Portland, Maine, United States
Greater Baltimore Medical Center and Cancer Center
🇺🇸Baltimore, Maryland, United States
Anne Arundel Oncology Center
🇺🇸Annapolis, Maryland, United States
Johns Hopkins Oncology Center
🇺🇸Baltimore, Maryland, United States
Cape Cod Hospital
🇺🇸Hyannis, Massachusetts, United States
McLaren Regional Cancer Center
🇺🇸Flint, Michigan, United States
Peninsula Regional Medical Center
🇺🇸Salisbury, Maryland, United States
Hurley Medical Center
🇺🇸Flint, Michigan, United States
Marquette General Hospital
🇺🇸Marquette, Michigan, United States
William Beaumont Hospital
🇺🇸Royal Oak, Michigan, United States
North Mississippi Medical Center/Cancer Center
🇺🇸Tupelo, Mississippi, United States
Cancer Research for the Ozarks
🇺🇸Springfield, Missouri, United States
St. Louis University Health Sciences Center
🇺🇸Saint Louis, Missouri, United States
Trinitas Hospital - Jersey Street Campus
🇺🇸Elizabeth, New Jersey, United States
Atlantic City Medical Center
🇺🇸Pomona, New Jersey, United States
Albert Einstein Comprehensive Cancer Center
🇺🇸Bronx, New York, United States
Fox Chase Cancer Center at Virtua Memorial Hospital Burlington County
🇺🇸Mount Holly, New Jersey, United States
Valley Hospital
🇺🇸Ridgewood, New Jersey, United States
Cancer Institute of New Jersey
🇺🇸New Brunswick, New Jersey, United States
St. Francis Medical Center
🇺🇸Trenton, New Jersey, United States
State University of New York Health Science Center at Brooklyn
🇺🇸Brooklyn, New York, United States
New York Methodist Hospital
🇺🇸Brooklyn, New York, United States
Associated Radiologists, P.A.
🇺🇸Warren, New Jersey, United States
Cancer Center of Albany Medical Center
🇺🇸Albany, New York, United States
Roswell Park Cancer Institute
🇺🇸Buffalo, New York, United States
CCOP - North Shore University Hospital
🇺🇸Manhasset, New York, United States
Beth Israel Medical Center
🇺🇸New York, New York, United States
Vassar Brothers Hospital
🇺🇸Poughkeepsie, New York, United States
Memorial Sloan-Kettering Cancer Center
🇺🇸New York, New York, United States
Herbert Irving Comprehensive Cancer Center
🇺🇸New York, New York, United States
Ireland Cancer Center
🇺🇸Cleveland, Ohio, United States
East Carolina University School of Medicine
🇺🇸Greenville, North Carolina, United States
Catawba Memorial Hospital
🇺🇸Hickory, North Carolina, United States
Trinity Cancer Care Center
🇺🇸Minot, North Dakota, United States
Akron General Medical Center
🇺🇸Akron, Ohio, United States
Christ Hospital
🇺🇸Cincinnati, Ohio, United States
Pocono Cancer Center
🇺🇸East Stroudsburg, Pennsylvania, United States
St. John Health System
🇺🇸Tulsa, Oklahoma, United States
Fitzgerald Mercy Hospital
🇺🇸Darby, Pennsylvania, United States
St. Anthony Hospital
🇺🇸Oklahoma City, Oklahoma, United States
Oklahoma University Medical Center
🇺🇸Oklahoma City, Oklahoma, United States
Delaware County Memorial Hospital
🇺🇸Drexel Hill, Pennsylvania, United States
Reading Hospital and Medical Center
🇺🇸Reading, Pennsylvania, United States
Wilkes Barre General Hospital
🇺🇸Wilkes-Barre, Pennsylvania, United States
Fox Chase Cancer Center
🇺🇸Philadelphia, Pennsylvania, United States
University of Pittsburgh Cancer Institute
🇺🇸Pittsburgh, Pennsylvania, United States
Mercy Hospital of Pittsburgh
🇺🇸Pittsburgh, Pennsylvania, United States
Western Pennsylvania Hospital
🇺🇸Pittsburgh, Pennsylvania, United States
Mercy Hospital Cancer Center - Scranton
🇺🇸Scranton, Pennsylvania, United States
Grand View Hospital
🇺🇸Sellersville, Pennsylvania, United States
CCOP - Greenville
🇺🇸Greenville, South Carolina, United States
Harrington Cancer Center
🇺🇸Amarillo, Texas, United States
CCOP - Upstate Carolina
🇺🇸Spartanburg, South Carolina, United States
CCOP - MainLine Health
🇺🇸Wynnewood, Pennsylvania, United States
Jackson-Madison County General Hospital
🇺🇸Jackson, Tennessee, United States
University of Tennessee, Memphis Cancer Center
🇺🇸Memphis, Tennessee, United States
University of Texas Medical Branch
🇺🇸Galveston, Texas, United States
Julie and Ben Rogers Cancer Institute
🇺🇸Beaumont, Texas, United States
Cancer Center at the University of Virginia
🇺🇸Charlottesville, Virginia, United States
Joe Arrington Cancer Research and Treatment Center
🇺🇸Lubbock, Texas, United States
Dixie Regional Medical Center
🇺🇸Saint George, Utah, United States
University of Texas - MD Anderson Cancer Center
🇺🇸Houston, Texas, United States
Vermont Cancer Center
🇺🇸Burlington, Vermont, United States
East Texas Medical Center - Cancer Institute
🇺🇸Tyler, Texas, United States
CCOP - Southwestern Vermont Regional Cancer Center
🇺🇸Bennington, Vermont, United States
Bayshore Medical Center
🇺🇸Pasadena, Texas, United States
RMH Regional Canter Center
🇺🇸Harrisonburg, Virginia, United States
Naval Medical Center, Portsmouth
🇺🇸Portsmouth, Virginia, United States
Schiffler Cancer Center
🇺🇸Wheeling, West Virginia, United States
Deaconess Medical Center
🇺🇸Spokane, Washington, United States
St. Vincent Hospital
🇺🇸Green Bay, Wisconsin, United States
Yakima Valley Memorial Hospital
🇺🇸Yakima, Washington, United States
Southern Wisconsin Radiotherapy Center
🇺🇸Madison, Wisconsin, United States
Gundersen Lutheran Medical Foundation
🇺🇸La Crosse, Wisconsin, United States
University of Wisconsin Comprehensive Cancer Center
🇺🇸Madison, Wisconsin, United States
Kingston Regional Cancer Centre
🇨🇦Kingston, Ontario, Canada
Toronto Sunnybrook Regional Cancer Centre
🇨🇦Toronto, Ontario, Canada
British Columbia Cancer Agency
🇨🇦Vancouver, British Columbia, Canada
Marshfield Clinic
🇺🇸Marshfield, Wisconsin, United States
Community Memorial Hospital
🇺🇸Menomonee Falls, Wisconsin, United States
Cancer Care Ontario-Hamilton Regional Cancer Centre
🇨🇦Hamilton, Ontario, Canada
Saint John Regional Hospital
🇨🇦Saint John, New Brunswick, Canada
Newfoundland Cancer Treatment and Research Foundation
🇨🇦St. Johns, Newfoundland and Labrador, Canada
Cancer Care Ontario-London Regional Cancer Centre
🇨🇦London, Ontario, Canada
Ottawa Regional Cancer Centre - General Campus
🇨🇦Ottawa, Ontario, Canada
Saskatoon Cancer Centre
🇨🇦Saskatoon, Saskatchewan, Canada
CHUS-Hopital Fleurimont
🇨🇦Fleurimont, Quebec, Canada
McGill University
🇨🇦Montreal, Quebec, Canada
Princess Margaret Hospital
🇨🇦Toronto, Ontario, Canada
CHU de Quebec - L'Hotel-Dieu de Quebec
🇨🇦Quebec City, Quebec, Canada
Allan Blair Cancer Centre
🇨🇦Regina, Saskatchewan, Canada
Barbara Ann Karmanos Cancer Institute
🇺🇸Detroit, Michigan, United States
University of Alabama at Birmingham Comprehensive Cancer Center
🇺🇸Birmingham, Alabama, United States
University of Colorado Cancer Center
🇺🇸Denver, Colorado, United States
Henry Ford Hospital
🇺🇸Detroit, Michigan, United States
CCOP - Columbia River Program
🇺🇸Portland, Oregon, United States
Mayo Clinic Cancer Center
🇺🇸Rochester, Minnesota, United States
Northeastern Ontario Regional Cancer Centre, Sudbury
🇨🇦Sudbury, Ontario, Canada
Northwestern Ontario Regional Cancer Centre, Thunder Bay
🇨🇦Thunder Bay, Ontario, Canada
Nebraska Health System
🇺🇸Omaha, Nebraska, United States
Methodist Cancer Center - Omaha
🇺🇸Omaha, Nebraska, United States
St. Joseph's Hospital
🇺🇸Milwaukee, Wisconsin, United States
Columbia Hospital
🇺🇸Milwaukee, Wisconsin, United States
St. Luke's Medical Center
🇺🇸Milwaukee, Wisconsin, United States
Veterans Affairs Medical Center - Milwaukee (Zablocki)
🇺🇸Milwaukee, Wisconsin, United States
LDS Hospital
🇺🇸Salt Lake City, Utah, United States
CCOP - Mount Sinai Medical Center
🇺🇸Miami Beach, Florida, United States
Bay Medical Center
🇺🇸Panama City, Florida, United States
Tallahassee Memorial Healthcare
🇺🇸Tallahassee, Florida, United States
MidMichigan Medical Center - Midland
🇺🇸Midland, Michigan, United States
CCOP - Kalamazoo
🇺🇸Kalamazoo, Michigan, United States
University of California San Diego Cancer Center
🇺🇸La Jolla, California, United States
Jonsson Comprehensive Cancer Center, UCLA
🇺🇸Los Angeles, California, United States
CCOP - Bay Area Tumor Institute
🇺🇸Oakland, California, United States
Cancer Care Center
🇺🇸Pomona, California, United States
York Hospital
🇺🇸York, Pennsylvania, United States
Southeastern Wisconsin Regional Cancer Center
🇺🇸Racine, Wisconsin, United States
Waukesha Memorial Hospital
🇺🇸Waukesha, Wisconsin, United States
Radiation Oncology Center - Sacramento
🇺🇸Sacramento, California, United States
H. Lee Moffitt Cancer Center and Research Institute
🇺🇸Tampa, Florida, United States
CCOP - Ann Arbor Regional
🇺🇸Ann Arbor, Michigan, United States
University of Michigan Comprehensive Cancer Center
🇺🇸Ann Arbor, Michigan, United States
CCOP - Southeast Cancer Control Consortium
🇺🇸Winston-Salem, North Carolina, United States
Comprehensive Cancer Center at Wake Forest University
🇺🇸Winston-Salem, North Carolina, United States
Bowman Gray School of Medicine
🇺🇸Winston-Salem, North Carolina, United States
Veterans Affairs Medical Center - Philadelphia
🇺🇸Philadelphia, Pennsylvania, United States
Kimmel Cancer Center of Thomas Jefferson University - Philadelphia
🇺🇸Philadelphia, Pennsylvania, United States
Martha Jefferson Hospital
🇺🇸Charlottesville, Virginia, United States
CCOP - Cancer Research for the Ozarks
🇺🇸Springfield, Missouri, United States
Riverhill Radiation Oncology
🇺🇸Yonkers, New York, United States
New York Medical College
🇺🇸Valhalla, New York, United States
Alabama Oncology, LLC
🇺🇸Montgomery, Alabama, United States
Cancer Center and Beckman Research Institute, City of Hope
🇺🇸Duarte, California, United States
David Grant Medical Center
🇺🇸Travis Air Force Base, California, United States
Halifax Medical Center
🇺🇸Daytona Beach, Florida, United States
Sarasota Radiation and Medical Oncology Center
🇺🇸Sarasota, Florida, United States
Gulf Coast Cancer Treatment Center
🇺🇸Panama City, Florida, United States
InterCommunity Cancer Center at Rome
🇺🇸Rome, Georgia, United States
Merle M. Mahr Cancer Center
🇺🇸Madisonville, Kentucky, United States
Central Baptist Hospital
🇺🇸Lexington, Kentucky, United States
Loyola University Medical Center
🇺🇸Maywood, Illinois, United States
Holden Comprehensive Cancer Center at The University of Iowa
🇺🇸Iowa City, Iowa, United States
William Beaumont Hospital - Troy
🇺🇸Troy, Michigan, United States
St. Mary's Medical Center
🇺🇸Saginaw, Michigan, United States
Mallinckrodt Institute of Radiology
🇺🇸Saint Louis, Missouri, United States
CCOP - Metro-Minnesota
🇺🇸Saint Louis Park, Minnesota, United States
Ellis Fischel Cancer Center - Columbia
🇺🇸Columbia, Missouri, United States
Monmouth Medical Center
🇺🇸Long Branch, New Jersey, United States
Finger Lakes Radiation Oncology, P.C.
🇺🇸Clifton Springs, New York, United States
Champlain Valley Physicians Hospital Medical Center
🇺🇸Plattsburgh, New York, United States
University of Rochester Cancer Center
🇺🇸Rochester, New York, United States
Meritcare Roger Maris Cancer Center
🇺🇸Fargo, North Dakota, United States
Northeast Medical Center
🇺🇸Concord, North Carolina, United States
Akron City Hospital
🇺🇸Akron, Ohio, United States
CCOP - Toledo Community Hospital Oncology Program
🇺🇸Toledo, Ohio, United States
CCOP - Dayton
🇺🇸Kettering, Ohio, United States
University Hospitals of Cleveland
🇺🇸Cleveland, Ohio, United States
Geisinger Medical Center
🇺🇸Danville, Pennsylvania, United States
St. Luke's Hospital Regional Cancer Center
🇺🇸Bethlehem, Pennsylvania, United States
Lehigh Valley Hospital
🇺🇸Allentown, Pennsylvania, United States
Penn State Geisinger Cancer Center
🇺🇸Hershey, Pennsylvania, United States
Roger Williams Medical Center/BUSM
🇺🇸Providence, Rhode Island, United States
Wilford Hall - 59th Medical Wing
🇺🇸Lackland Air Force Base, Texas, United States
University of Florida Health Science Center
🇺🇸Gainesville, Florida, United States
MD Anderson Cancer Center Orlando
🇺🇸Orlando, Florida, United States
James Graham Brown Cancer Center
🇺🇸Louisville, Kentucky, United States
MBCCOP - LSU Health Sciences Center
🇺🇸New Orleans, Louisiana, United States
Louisville Radiation Oncology
🇺🇸Louisville, Kentucky, United States
CCOP - Kansas City
🇺🇸Kansas City, Missouri, United States
Tulane University School of Medicine
🇺🇸New Orleans, Louisiana, United States
Lineberger Comprehensive Cancer Center, UNC
🇺🇸Chapel Hill, North Carolina, United States
Medical University of South Carolina
🇺🇸Charleston, South Carolina, United States
Bon-Secours - St. Mary's Hospital
🇺🇸Richmond, Virginia, United States
Massey Cancer Center
🇺🇸Richmond, Virginia, United States
University of Arkansas for Medical Sciences
🇺🇸Little Rock, Arkansas, United States
Saint Joseph Medical Center
🇺🇸Albuquerque, New Mexico, United States
Medical Center/John B. Amos Community Cancer Center
🇺🇸Columbus, Georgia, United States
Rapid City Regional Hospital
🇺🇸Rapid City, South Dakota, United States
Community Medical Center
🇺🇸Toms River, New Jersey, United States
Veterans Affairs Medical Center - Boston (Jamaica Plain)
🇺🇸Jamaica Plain, Massachusetts, United States