Long Term Outcomes After Visceral Aortic Endarteriectomy for Coral Reef Lesion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Major adverse cardiac event (MACE)
研究概览
简要总结
Coral reef aorta is defined by a calcified stenosis of the visceral aorta which can cause leg claudication, renal failure and visceral ischemia depending the type and localisation of the stenosis.
This pathology is rare and is usually treated by open surgery with aortic endarteriectomy. Little is know about the outcomes after such aggressive surgery with short series and short follow up.
The authors propose a retrospective study from their institution to explore the post operative and long term outcomes after this surgery.
详细描述
Coral reef aorta is defined by a calcified stenosis of the visceral aorta which can cause leg claudication, renal failure and visceral ischemia depending the type and localisation of the stenosis.
This pathology is rare and is usually treated by open surgery with aortic endarteriectomy.
Little is known in the literature regarding the outcomes of this aggressive surgery.
The authors propose a retrospective study from their institution describing the type of surgery realised. They describe the post operative outcomes of this surgery in term of cardiologic, respiratory, renal complication a,d surgical complication.
Moreover they follow the patients to present long term outcomes of this pathology with a description of the post operative recurrence of a coral reef, the permeability of the different target vessel and the cardiologic, respiratory and renal evolution of the different patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Coral reef surgery
- •Urgent intervention
- •Claudication, renal, visceral involvement
- •Thoracic aortic cross clamping (above coeliac trunk)
排除标准
- •"simple" visceral aorto thrombectomy without opening laterally the aorta
结局指标
主要结局
Major adverse cardiac event (MACE)
时间窗: 1 month after surgery
Post operative cardiologic complication
Reintervention
时间窗: 1 month after surgery
Need of reintervention before discharge
次要结局
- Long term follow up(1 month, 1 year, yearly up to 5 years)
- Target vessel patency(1 month, 1 year, yearly up to 5 years)
- Kidney function evolution(1 month, 1 year, yearly up to 5 years)
研究者
Aurélien Hostalrich
MD,PhD Principal investigator
University Paul Sabatier of Toulouse