Markers in Follicular Fluid and in Embryo Culture Medium as a Marker of Oocyte and Embryo Quality
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 220
- 试验地点
- 1
- 主要终点
- Different markers discriminating the studied groups.
研究概览
简要总结
Assessment of the quality of follicular fluid and early embryo via chemical markers.
详细描述
The selectin of an embryo for transfer is currently based on detailed morphological assessment and scoring system. morhpokinetics introduced recently to IVF laboratories can define annotations and provide an algorithm for optimal cleavage rates and embryonic development. however more data and validations are requested when it comes to choosing the best single embryo from a cohort of available similarly graded embryos. Consequently, non-invasive quantitative methods for embryo selection prior to transfer have been sought. In the current study metabolic profile of follicular fluid and the embryos produced in IVF procedure will be assessed
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Patients undergoing IVF procedures at Carmel Medical Center and are able to sign an informed consent form.
- •Female patients age 18-45
排除标准
- •Women with any malignancy
- •Patient's request to be withdrawn from the study.
结局指标
主要结局
Different markers discriminating the studied groups.
时间窗: two years
High correlation between the studied markers and the currently used morphological assessment of the quality of embryos and oocytes will define the potential of the studied markers as a mean for embryo and quality assessment. The current study is pioneer in the field of assessment of embryos and follicles and this group of markers have not been studied previously, therefore we prefer not to clarify more details
次要结局
未报告次要终点