TCTR20191207001
Completed
Phase 2
Very low dose of lidocaine attenuates fentanyl induced cough: A double blind randomized controlled trial
Phramongkutklao Hospital and Collage of Medicine0 sites320 target enrollmentDecember 7, 2019
ConditionsFentanyl-induced cough is commonly occurred, especially in pre anesthetic induction between 18% and 65% and lidocaine can alleviate the incidence and severity of cough. Therefore, the objective of the present study was to demonstrate efficacy of low dosage of lidocaine attenuate FICCough, Fenanyl, Lidocaine, low dose
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Fentanyl-induced cough is commonly occurred, especially in pre anesthetic induction between 18% and 65% and lidocaine can alleviate the incidence and severity of cough. Therefore, the objective of the present study was to demonstrate efficacy of low dosage of lidocaine attenuate FIC
- Sponsor
- Phramongkutklao Hospital and Collage of Medicine
- Enrollment
- 320
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •ASA class 1\-2
Exclusion Criteria
- •Patients were unwilling to participate, had a history of allergy to lidocaine or fentanyl, history of chronic obstructive pulmonary disease, bronchial asthma, recent respiratory tract infection less than 2 weeks, impaired kidney or liver function, or had been treated with angiotensin converting enzyme inhibitors or beta blocker, symptomatic bradycardia, tachyarrhythmia, left bundle branch block and second or third\-degree atrioventricular block, pregnancy and language barrier.
Outcomes
Primary Outcomes
Not specified
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