To access the effects of two group of drug combination on hemp dynamic changes during tracheal intubation
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/10/058692
- Lead Sponsor
- non
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patient with the history of difficult intubation
2. Patient with anticipated difficult airway
3. Patients having history of endocrine, cardiovascular, renal or CNS disease.
4. Patient having BMI > 30 kg m-2
5. Patient on anti-hypertensive or narcotic drugs
Exclusion Criteria
1. Patient with the history of difficult intubation
2. Patient with anticipated difficult airway
3. Patients having history of endocrine, cardiovascular, renal or CNS disease.
4. Patient having BMI > 30 kg m-2
5. Patient on anti-hypertensive or narcotic drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the heart rate & systolic blood pressure of two groups following laryngoscopy & intubation.Timepoint: i. Preoperative (baseline values) i.e. before injection of study drug <br/ ><br>ii. Before induction of anaesthesia (after injection of study drug) <br/ ><br>iii. After induction of anaesthesia i.e. just before laryngoscopy & intubation <br/ ><br>iv. Post intubation at 0min, 1 min, 2 min, 3min, 5min, 7min, 10min and 15min <br/ ><br>v. Then every 15 min till the end of surgery
- Secondary Outcome Measures
Name Time Method 1. To compare the diastolic & mean blood pressure following laryngoscopy & intubation between two groups <br/ ><br>2. To compare post-operative pain by VAS score <br/ ><br>3. To compare post-operative sedation score <br/ ><br> ?Timepoint: Post intubation at 0min, 1 min, 2 min, 3min, 5min, 7min, 10min & 15min <br/ ><br>v. Then every 15 min till the end of surgery <br/ ><br> <br/ ><br>1. Haemodynamic parameters (HR, SBP, DBP, MAP, SpO2) will be recorded at 0 min, then every 15 minutes for 1 hour and then every hour for next 2 hours post operatively. <br/ ><br>2. Following post-operative parameters will be recorded at 0, 1, 2, & 3 hrs <br/ ><br>i) Pain (VAS) score <br/ ><br>ii) Sedation score <br/ ><br>