europsychological Assessment of Cognitive Impairment in Kidney Transplantation (NAsKiT) and its Related Risk Factors
Recruiting
- Conditions
- N18.5Chronic kidney disease, stage 5
- Registration Number
- DRKS00029164
- Lead Sponsor
- niversitätsklinikum Giessen und Marburg, Standort Giessen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Individuals who are going to receive a kidney transplantation (immediate – deceased kidney donor, or within the next two weeks – living kidney donors) or have already received a kidney transplantation in the past will be included in this study. Due to the use of a standardized psychological assessment, individuals have to be native German speakers and at least 18 years of age.
Exclusion Criteria
Individuals under the legal supervision of a caretaker and with preexisting psychiatric disorder have to be excluded from the study.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measure will be a) the effect of kidney transplantation of the cognitive performance up to 12 months after transplantation (part A) and b) the development of cognitive performance following kidney transplantation over time (part B).
- Secondary Outcome Measures
Name Time Method As a secondary outcome, we will assess a distinct profile of cognitive function using standard neurocognitive tests. Furthermore, we explore the impact and temporal development of a set of risk factors for deficits in cognitive performance. Second, we want to examine the extent to which cognitive impairment affects depression at all follow-up time points. Third, we want to assess how stressors negatively or positively affect cognitive performance. Fourth, we want to investigate to what degree cognitive performance affects the formation and development of donor-specific antibodies.