Prospective and exploratory study for disease specific biomarkers and objective indicators in neurodegenerative diseases

Not Applicable

Recruiting

• Conditions: All Neurodegenerative diseases specifically Parkinson' s disease, corticobasal degeneration and progressive supranuclear palsy

• Registration Number: JPRN-UMIN000036570
• Lead Sponsor: Department of Neurology, Osaka University Graduate School of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-22
• Last Update Posted: 17 October 2023
• Study Completion: 2025-03-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

Not provided

Exclusion Criteria

None

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of parkinsonism (MDS-UPDRS score, Hoehn-Yahr stage)

Secondary Outcome Measures

Name	Time	Method
Cognitive evaluation (MMSE, Visual Perspective test, etc.), Brain imaging evaluation (structural MRI , functional MRI, etc.) and biochemical markers of cerebrospinal fluid and serum (catecholamine concentration, alpha-synuclein concentration, cerebrospinal fluid amyloid aggregation, etc.)