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Exploration of the effects of HFS-induced secondary hyperalgesia on the NDT-EP method

Recruiting
Conditions
one
Registration Number
NL-OMON25830
Lead Sponsor
niversity of Twente
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

(1) A signed, written informed consent; (2) Age between 16 and 40

Exclusion Criteria

(1) Participant refusal during the study; (2) Language problems; (3) Skin problems at site of stimulation or EEG recording; (4) Diabetes; (5) Implanted stimulation device; (6) Pregnancy; (7) Usage of analgesics within 24 hours before the experiment; (8) Excessive consumption of alcohol or drugs within 24 hours before the experiment; (9) Pain complaints at the time of the experiment; (10) (A medical history of) chronic pain

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
(1) Nociceptive Detection Thresholds (NDTs)<br>(2) EEG signals<br>(3) Numerical Rating Scale to mechanical punctate stimulation
Secondary Outcome Measures
NameTimeMethod
(1) Participant characteristics (Age, sex, handedness)<br>(2) Response time to stimuli<br>(3) Electrode-skin impedance
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