The effect of peri-operative anti-inflammatory treatment on postoperative muscle weakness and muscle fatigue in elderly elective surgery patients

Completed

• Conditions: Post-operative muscle weakness, fatigue and inflammation; Musculoskeletal Diseases; Other specified disorders of muscle

• Registration Number: ISRCTN51508868
• Lead Sponsor: Vrije University Brussels [Vrije Universiteit Brussel] (Belgium)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-11-09
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

All elderly (male or female, aged > 60 years) elective abdominal surgery patients

Exclusion Criteria

1. Unavailable one day before the surgical intervention
2. Presenting important inflammation preoperatively C-reactive protein (CRP)>10mg/L
3. Unable to understand or execute the test instructions due to cognitive impairment mini mental state examination (MMSE<23 / 30) and/or physical disability
4. Already using selective tumor necrosis factor (TNF)-alpha inhibitors, nitric oxide donors, fibrates, non-steroidal anti-inflammatory drugs (NSAID?s) or corticosteroids or when contra-indications for the use of one of these products exist

Study & Design

• Study Type: Interventional
• Study Design: Not specified