Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients

Not Applicable

Not yet recruiting

• Conditions: Tobacco Use Disorder

• Registration Number: NCT07164404
• Lead Sponsor: Medical University of South Carolina

Brief Summary

Investigators are evaluating an EHR-based, non-interruptive alert to increase NRT prescribing in the hospital and at discharge for hospitalized patients. Investigators will investigate two randomized groups of resident physicians to evaluate their prescribing behaviors when the tool is introduced.

Detailed Description

Efforts to decrease cancer-related morbidity and mortality include increasing smoking cessation, however smoking remains prevalent. Classically, alerts within the electronic health record (EHR) are implemented to address gaps in care, yet studies suggest typical EHR alerts are often overridden and ignored. In this study, the investigators aim to decrease the incidence and burden of disease by including hospitalists as part of the multidisciplinary care team by implementing and evaluating a novel non-interruptive EHR alert embedded within a provider note as a tool to increase prescription of nicotine replacement therapy to patients who smoke upon admission to and discharge from the hospital. Investigators will investigate two randomized groups of resident physicians to evaluate their prescribing behaviors when the tool is introduced.

Study Timeline

• Study First Submitted: 2025-08-28
• Status Verified: 2025-09
• Study First Submitted QC: 2025-09-07
• Study First Posted: 2025-09-10
• Last Update Submitted: 2025-09-11
• Last Update Posted: 2025-09-17
• Study Start: 2025-10-01
• Primary Completion: 2026-01
• Study Completion: 2026-01-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 220

Inclusion Criteria

• Hospitalized patients admitted to a General Medicine Service at MUSC Charleston
• Identified as actively smoking tobacco via nursing admission screening
• Admitted by a resident physician participating in the study (as indicated by the H&P note)

Exclusion Criteria

• None

Resident Physicians:

Inclusion Criteria:

• Internal medicine resident physicians rotating on the hospitalist service at MUSC Health Charleston

Exclusion Criteria:

• None

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Nicotine Replacement Therapy (NRT) prescribing rates during hospitalization	During hospitalization, assessed from admission to discharge (average of 3-7 days)
Nicotine Replacement Therapy (NRT) prescribing rates at discharge	During hospitalization, assessed from admission to discharge (average of 3-7 days)
Rate of referral to outpatient tobacco cessation clinic	During hospitalization, assessed from admission to discharge (average of 3-7 days)

Trial Locations

Locations (1)

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States