Pilot study investigating the efficiency and effectiveness of a clinic that is designed to remove penicillin allergy from low-risk patients who believe they are allergic to penicilli

Not Applicable

• Conditions: Participants currently labelled with a penicillin allergy who are screened as low risk; Not Applicable

• Registration Number: ISRCTN79913496
• Lead Sponsor: orthern Ontario Academic Medicine Association

Brief Summary

Other publications see attached file 43171 Data Acquisition Sheet DOC Wilson Dec 15.pdf Data Acquisition Sheet (added 07/02/2023) Other publications see attached file 43171 Participant Feedback Survey DOC Wilson.pdf Participant Feedback Survey (added 07/02/2023) Other publications see attached file 43171 Participant Questionnaire for 6 and 12 months.pdf Participant Questionnaire for 6 and 12 months (added 07/02/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-02-07
• Last Update Posted: 11 March 2024
• Study Completion: 2026-03-02

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

All participants who attend the DOC are eligible to provide feedback. To participate in the DOC there are eligibility requirements to ensure participants are at low risk of an allergic response. Whether attendees complete the DOC or not they will be asked to provide feedback and satisfaction regarding the clinic.

Low risk for penicillin allergy:
1. No penicillin reaction in the past 10 years
2. Never hospitalized with a reaction to penicillin
3. No evidence of a severe cutaneous adverse reaction (SCAR)
4. No evidence of drug-related eosinophilia and systemic symptoms (DRESS)
5. No history of asthma
6. Cannot recall nature of reaction or history of isolated non-allergic symptoms (e.g., GI upset only) or pruritus only without rash or simple macular papular rash as a child with amoxicillin
7. Only a family history of reaction
8. No history of IgE-mediated hypersensitivity reaction or angioedema

Exclusion Criteria

For the data collection there are no exclusion criteria. The DOC excludes moderate and high-risk allergy participants. Additionally, any sign of a reaction within the clinic would disqualify the participant from further participation. However, the research study will request those participants' feedback.

Study & Design

• Study Type: Observational
• Study Design: Not specified