Comparison of Tranexamic Acid and Nitroglycerine and Remifentanil in prevention of bleeding during herniated lumbar intervertebral disc surgery
Phase 3
Recruiting
- Conditions
- Herniated lumbar intervertebral disc.Other intervertebral disc displacement, lumbar regionM51.26
- Registration Number
- IRCT20141209020258N159
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 135
Inclusion Criteria
Age 18 to 60 years
ASA class 1 and 2
No coagulation disorders
No history of cardiovascular disease
Proper control of blood pressure
Absence of pregnancy
Not addicted to opioids
Body mass index more than 35
No family history of thromboembolism
Exclusion Criteria
Dissatisfaction with surgery
Existence of allergy to the studied drugs
Presence of plasma creatinine more than 1/5
Platelet count less than 150 thousand
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding. Timepoint: During surgery. Method of measurement: Physical examination.;Surgeon consent. Timepoint: During surgery. Method of measurement: Observation.
- Secondary Outcome Measures
Name Time Method