The intradialytic clearance of polyclonal immunoglobulin free light chains by low-flux hemodialysis, high-flux hemodialysis and online hemodiafiltration .
- Conditions
- End stage renal diseaseinfections100276651000401810038430
- Registration Number
- NL-OMON35927
- Lead Sponsor
- Maasstadziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Prevalent hemodialysis patients, treated with hemodialysis 3 times a week (for at least 2 months) with a minimum dialysis urea Kt/V >= 1.2 and who are able to understand the study procedures.
Exclusion Criteria
Exclusion criteria are age < 18 years, treatment by hemodiafiltration or high-flux hemodialysis in the 6 months preceding entering this study, severe incompliance defined as non-adherence to the dialysis prescription and a life expectancy < 3 months due to causes other than kidney disease. Hemoglobin level < 6.0 mmol/L.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The difference in change of immunoglobulin free light chain serum concentration<br /><br>during the hemodialysis session. </p><br>
- Secondary Outcome Measures
Name Time Method <p>N.a.</p><br>