Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing
- Conditions
- Endodontic Disease
- Interventions
- Other: Using ethylenediaminetetraacetic acid (EDTA), citric acid ((MONO/ANH) and etidronic acid (HEBP) to clean root canals during regenerative endodontic treatments
- Registration Number
- NCT06386991
- Lead Sponsor
- TC Erciyes University
- Brief Summary
In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used. These solutions; Ethylene Diamine Tetra Acetic Acid (EDTA), Etidronic Acid and Citric Acid. The aim of this study is to evaluate the effect of different irrigation solutions used in regenerative endodontic treatment of necrotic open apex molar teeth on postoperative pain. Additionally, the healing of these teeth will be monitored for 1 year.
- Detailed Description
Root canal treatment is a treatment method applied to milk and permanent teeth. The inflamed and necrotic pulp where the root canal is located is cleaned, debrided chemo-mechanically, and finally filled hermetically with a biocompatible material. Necrotic immature teeth lose their restorative and defensive abilities. Since the root canal walls of these teeth are thin and weak, regenerative endodontic procedures are applied more frequently in the treatment of immature teeth to ensure root development and to restore the vitality of the pulp tissue. In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used. These solutions; Ethylene Diamine Tetra Acetic Acid (EDTA), Etidronic Acid and Citric Acid. The aim of this study is to evaluate the effect of different irrigation solutions used in regenerative endodontic treatment of necrotic open apex molar teeth on postoperative pain. Additionally, the healing of these teeth will be monitored for 1 year.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 39
• Molars with open apex
- Teeth with apical periodontitis
- Teeth for which prosthetic restoration is not planned
- Patients between the ages of 8-15 who do not have any significant health problems
- Patients who are not accompanied by periodontal problems and have good oral hygiene
• People with systemic disease and allergic reactions
- Severely damaged teeth
- If the tooth has previously undergone root canal treatment.
- Use of antibiotics, anti-inflammatory and painkillers in the last two weeks
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Ethylenediamine tetraacetic acid (EDTA) Using ethylenediaminetetraacetic acid (EDTA), citric acid ((MONO/ANH) and etidronic acid (HEBP) to clean root canals during regenerative endodontic treatments Regenerative endodontic treatments require the use of irrigation solutions to break down inorganic and organic tissue residues in the root canals. Sodium hypochlorite (NaOCl) and Ethylenediamine tetraacetic acid (EDTA)will be used when disinfecting root canals. (GROUP 1) ETİDRONİC ACID (HEBP) Using ethylenediaminetetraacetic acid (EDTA), citric acid ((MONO/ANH) and etidronic acid (HEBP) to clean root canals during regenerative endodontic treatments Regenerative endodontic treatments require the use of irrigation solutions to break down inorganic and organic tissue residues in the root canals. Sodium hypochlorite (NaOCl) and ETİDRONİC ACID (HEBP) be used when disinfecting root canals. (GROUP 3) CITRIC ACID (MONO/ANH) Using ethylenediaminetetraacetic acid (EDTA), citric acid ((MONO/ANH) and etidronic acid (HEBP) to clean root canals during regenerative endodontic treatments Regenerative endodontic treatments require the use of irrigation solutions to break down inorganic and organic tissue residues in the root canals. Sodium hypochlorite (NaOCl) and CITRIC ACID (MONO/ANH) be used when disinfecting root canals. (GROUP 2)
- Primary Outcome Measures
Name Time Method Determining and recording pain levels on the pain scale between treatment sessions 2 weeks Evaluations close to 100 on the postoperative pain scale indicate that the severity of pain increases. Evaluations close to 0 indicate that the severity of pain has decreased.
- Secondary Outcome Measures
Name Time Method In the follow-up sessions after the treatment, the size of the lesion in the bone (mm2) is measured by radiography. 2 years Evaluations close to 100 on the scale following lesion healing indicate that the lesion size has increased. Evaluations close to 0 indicate that the lesion size has decreased.
Trial Locations
- Locations (1)
Erciyes Üniversitesi Diş Hekimliği Fakültesi
🇹🇷Kayseri, Turkey