Evaluation of the Effects of Different Irrigation Solutions Used in Regenerative Endodontic Treatment of Lower Molars With Open Necrotic Apexes on Postoperative Pain and Lesion Healing
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 39
- 试验地点
- 2
- 主要终点
- Determining and recording pain levels on the pain scale between treatment sessions
研究概览
简要总结
In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used. These solutions; Ethylene Diamine Tetra Acetic Acid (EDTA), Etidronic Acid and Citric Acid. The aim of this study is to evaluate the effect of different irrigation solutions used in regenerative endodontic treatment of necrotic open apex molar teeth on postoperative pain. Additionally, the healing of these teeth will be monitored for 1 year.
详细描述
Root canal treatment is a treatment method applied to milk and permanent teeth. The inflamed and necrotic pulp where the root canal is located is cleaned, debrided chemo-mechanically, and finally filled hermetically with a biocompatible material. Necrotic immature teeth lose their restorative and defensive abilities. Since the root canal walls of these teeth are thin and weak, regenerative endodontic procedures are applied more frequently in the treatment of immature teeth to ensure root development and to restore the vitality of the pulp tissue. In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used. These solutions; Ethylene Diamine Tetra Acetic Acid (EDTA), Etidronic Acid and Citric Acid. The aim of this study is to evaluate the effect of different irrigation solutions used in regenerative endodontic treatment of necrotic open apex molar teeth on postoperative pain. Additionally, the healing of these teeth will be monitored for 1 year.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 8 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Molars with open apex
- •Teeth with apical periodontitis
- •Teeth for which prosthetic restoration is not planned
- •Patients between the ages of 8-15 who do not have any significant health problems
- •Patients who are not accompanied by periodontal problems and have good oral hygiene
排除标准
- •People with systemic disease and allergic reactions
- •Severely damaged teeth
- •If the tooth has previously undergone root canal treatment.
- •Use of antibiotics, anti-inflammatory and painkillers in the last two weeks
结局指标
主要结局
Determining and recording pain levels on the pain scale between treatment sessions
时间窗: 2 weeks
Evaluations close to 100 on the postoperative pain scale indicate that the severity of pain increases. Evaluations close to 0 indicate that the severity of pain has decreased.
次要结局
- In the follow-up sessions after the treatment, the size of the lesion in the bone (mm2) is measured by radiography.(2 years)
研究者
Ipek Eraslan Akyuz
research assistant
TC Erciyes University