se of oral tizanidine in laparoscopic abdominal surgeries
Not Applicable
- Conditions
- Health Condition 1: K800- Calculus of gallbladder with acutecholecystitisHealth Condition 2: N719- Inflammatory disease of uterus, unspecifiedHealth Condition 3: K358- Other and unspecified acute appendicitis
- Registration Number
- CTRI/2023/07/055621
- Lead Sponsor
- Fortis Escorts Hospital Faridabad
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age 18-60 years
2.ASA status I and II
3.BMI less than 35
Exclusion Criteria
1. ASA status more than II
2.BMI more than 35
3. Laparoscopic hernia repair surgeries
4.Emergency cases
5. Allergy to tizanidine
6. History of alcohol consumption
7. Patients on treatment with beta-blockers, digoxin, anticonvulsants, antihypertensive drugs, sedatives or α2 agonists
8. CNS disorders
9. Renal or hepatic insufficiency
10. Peptic ulcer
11. Hypertension
12. Patients with chronic pain
13. Bleeding disorders
14. Sleep disturbances
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The total dose of fentanyl consumed intra-operatively will be noted.Timepoint: 60-128mins
- Secondary Outcome Measures
Name Time Method â?¢ Post-operative pain will be evaluated using VAS on arrival in PACU, at 2 h, 6 h, 12 h <br/ ><br>after surgery. <br/ ><br>â?¢ The time for the first request for rescue analgesia will be noted. <br/ ><br>â?¢ Incidence of side effects such as headache, dry mouth, dizziness, nausea, vomiting & bradycardia will be noted.Timepoint: 1. POST OP PAIN SCORES AT ARRIVAL AT PACU, 2HR, 6HR, 12HR <br/ ><br>2. INCIDENCE OF SIDE EFFECTS AT ARRIVAL AT PAC