Effects of Tizanidine on sinus endoscopy bleeding
Not Applicable
- Conditions
- Condition 1: Nasal polyposis. Condition 2: Nasal polyp.Polyp of nasal cavity
- Registration Number
- IRCT2016022625481N2
- Lead Sponsor
- Vice Chancellor for research of Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Age more than 16 years undergoing endoscopic sinus surgery • ASA class I and II
Exclusion criteria : • high blood pressure (severe) • liver or kidney disease •coagulopathy • Diabetes • Abnormal blood sugar on the morning of the day of surgery • severe hypotension during surgery that requires intravenous administration of large volumes • Lack of consent to participate in the study have. Aspirin or any anticoagulants drugs. hemoglobin under 10.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding. Timepoint: after 1 hour. Method of measurement: check list.;Severity of nasal sinus bleeding. Timepoint: before induction, after induction, 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80 minutes. Method of measurement: heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure.
- Secondary Outcome Measures
Name Time Method Surgeon consent. Timepoint: based on Likert scale. Method of measurement: It will be measured based on a verbal descriptive scale which is related with a visual bleeding score.