To assess the effect of early enteral feeding VS delayed enteral Feeding in mild and moderate acute pancreatitis patients in a tertiary care hospital in puducherry
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 88
- Locations
- 1
- Primary Endpoint
- To assess the effect of early vs delayed enteral feeding in mild and moderate acute pancreatitis
Study Overview
Brief Summary
The study is plan to conducted in IGMC&RI in the department of General medicine among mild and moderate acute pancreatitis based on Balthazar CT severity index the patients were divided by simple randomization into 2 groups as A & B. Group A receives early enteral feeding ( within 24 hours) and Group B receives delayed enteral feeding ( after 48 hours ). SOFA and BUN/Albumin ratio will be measured in both the groups at the time of admission, Enteral nutrition: 25- 30 Kcal / kg/ day , 200 – 300 ml, 5-6 times /day, Intermittent bolus Feeds were commenced at full strength and a rate of 30 ml/h increasing to 100 ml/h over 24–48 h. SOFA score and BUN/Albumin ratio will be measured in both the groups after 4 days of admission . Assess the effect of early vs delayed enteral nutrition in view of reducing the systemic/local complication, organ failure and length of hospital stay.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 20.00 Year(s) to 70.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Age more than or equal to 20 years including both the sexes who are diagnosed as mild and moderate pancreatitis based on Balthazar CT severity index ( score less than 7) at the time of admission.
Exclusion Criteria
- •Age less than 20 years chronic pancreatitis severe acute pancreatitis based on Balthazar CT severity index ( score more than 7) pancreatic cancer shock at the time of presentation (systolic BP less than 90 mm hg) Patients with co-morbidities like COPD, Renal impairment Pregnant women patient with known history of allergy to iodinated contrast agents All patients who will not give consent for study.
Outcomes
Primary Outcomes
To assess the effect of early vs delayed enteral feeding in mild and moderate acute pancreatitis
Time Frame: Day 1 and day 4
Secondary Outcomes
- To assess the BUN/albumin ratio as severity predictors in acute pancreatitis.(Day 4)
Investigators
Jayasti.P
Indira Gandhi medical College and research institute , Kathirkamam, puducherry