To assess the effect of early enteral feeding VS delayed enteral Feeding in mild and moderate acute pancreatitis patients in a tertiary care hospital in puducherry
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- To assess the effect of early vs delayed enteral feeding in mild and moderate acute pancreatitis
研究概览
简要总结
The study is plan to conducted in IGMC&RI in the department of General medicine among mild and moderate acute pancreatitis based on Balthazar CT severity index the patients were divided by simple randomization into 2 groups as A & B. Group A receives early enteral feeding ( within 24 hours) and Group B receives delayed enteral feeding ( after 48 hours ). SOFA and BUN/Albumin ratio will be measured in both the groups at the time of admission, Enteral nutrition: 25- 30 Kcal / kg/ day , 200 – 300 ml, 5-6 times /day, Intermittent bolus Feeds were commenced at full strength and a rate of 30 ml/h increasing to 100 ml/h over 24–48 h. SOFA score and BUN/Albumin ratio will be measured in both the groups after 4 days of admission . Assess the effect of early vs delayed enteral nutrition in view of reducing the systemic/local complication, organ failure and length of hospital stay.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Age more than or equal to 20 years including both the sexes who are diagnosed as mild and moderate pancreatitis based on Balthazar CT severity index ( score less than 7) at the time of admission.
排除标准
- •Age less than 20 years chronic pancreatitis severe acute pancreatitis based on Balthazar CT severity index ( score more than 7) pancreatic cancer shock at the time of presentation (systolic BP less than 90 mm hg) Patients with co-morbidities like COPD, Renal impairment Pregnant women patient with known history of allergy to iodinated contrast agents All patients who will not give consent for study.
结局指标
主要结局
To assess the effect of early vs delayed enteral feeding in mild and moderate acute pancreatitis
时间窗: Day 1 and day 4
次要结局
- To assess the BUN/albumin ratio as severity predictors in acute pancreatitis.(Day 4)
研究者
Jayasti.P
Indira Gandhi medical College and research institute , Kathirkamam, puducherry